2421 Results for: "STEMCELL Technologies"

Supplier: STEMCELL Technologies

Mouse monoclonal IgG1 antibody against human epithelial cells, unconjugated.

Supplier: STEMCELL Technologies

Rat monoclonal IgG2a antibody against mouse CD19, unconjugated.

Supplier: STEMCELL Technologies

For hydrolysis of hyaluronic acid.

Supplier: STEMCELL Technologies

Animal component-free collagenase for the digestion of native collagen fibrils.

Supplier: STEMCELL Technologies

Mouse monoclonal IgG2b, kappa isotype control antibody, Alexa Fluor® 488-conjugated.

Supplier: STEMCELL Technologies

Rat monoclonal IgG2a antibody against human, mouse, rhesus CD49f, APC-conjugated.

Supplier: STEMCELL Technologies

Mouse monoclonal IgG1 antibody against human epithelial cells, FITC-conjugated.

Supplier: STEMCELL Technologies

Mouse monoclonal IgM antibody against human, rhesus, rabbit TRA­1­60 (podocalyxin), Alexa Fluor® 488-conjugated.

Supplier: STEMCELL Technologies

Mouse monoclonal IgG1 antibody against human, rhesus, cynomolgus CD83, APC-conjugated.

Supplier: STEMCELL Technologies

Mouse monoclonal IgG1 antibody against human CD56 (NCAM), unconjugated.

Supplier: STEMCELL Technologies

cGMP, feeder-free maintenance medium for human ES and iPS cells.

Supplier: STEMCELL Technologies

Propidium Iodide (PI) is a red-fluorescent cell viability dye which is excluded from live cells with intact membranes, but penetrates dead or damaged cells and binds to DNA and RNA by intercalating between the bases.

Supplier: STEMCELL Technologies

Mouse monoclonal IgG2a, kappa isotype control antibody, unconjugated.

Supplier: STEMCELL Technologies

Mouse monoclonal IgG2a, kappa isotype control antibody, FITC-conjugated.

Supplier: STEMCELL Technologies

Rat monoclonal IgG2b antibody against mouse EPCR (CD201), PE-conjugated.

Supplier: STEMCELL Technologies

Complete kit for hematopoietic CFU assays.

Supplier: STEMCELL Technologies

Culture supplement for the differentiation of human naïve CD4+ T cells into Th1 cells.

Supplier: STEMCELL Technologies

Hamster (Armenian) monoclonal IgG antibody against mouse CD11c, biotin-conjugated.

Supplier: STEMCELL Technologies

Hamster (Armenian) monoclonal IgG antibody against mouse CD11c.

Supplier: STEMCELL Technologies

Rat monoclonal IgG2a antibody against mouse Ly-6G, Pacific Blue™-conjugated.

Supplier: STEMCELL Technologies

The principal physiological regulator of erythropoiesis, Erythropoietin (EPO) is a glycoprotein growth factor that is produced primarily in the kidney in response to hypoxia or anemia. EPO promotes erythropoiesis by binding to a homodimeric cell surface receptor that activates JAK2/STAT5, PI3K/AKT, and MAPK pathways, and stimulates the proliferation and differentiation of erythroid progenitor cells (Jelkmann. Transfus Med Hemother, 2013; Kuhrt and Wojchowski. Blood, 2015).

Supplier: STEMCELL Technologies

Betacellulin is a member of the epidermal growth factor (EGF) family, and signals through EGF receptor and ERBB4. It activates ERK and AKT pathways, which induces neural stem cell proliferation and prevents spontaneous differentiation in culture. Betacellulin stimulates the expansion of neural stem cells, transit-amplifying cells, and neuroblasts derived from subventricular zone and dentate gyrus (Gómez-Gaviro et al.). It is a potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells. Betacellulin down-regulates E-cadherin expression in ovarian cancer cell lines via MEK/ERK1/2 and PI3K/AKT signaling pathways, thus increasing cell migration (Zhao et al.). It is a modulator of interferon (IFN) response and enhances anti-viral effects of IFN (Al-Yahya et al.). Betacellulin is expressed in pancreatic α cells, β cells, and duct cells. It induces the proliferation of pancreatic cancer cell lines, inhibits apoptosis, promotes the neogenesis of β cells, and converts non-β cells into insulin-producing cells (Kawaguchi et al.; Miyagawa al.; Saito et al.).

Supplier: STEMCELL Technologies

Amine-labelling fluorescent dye for live/dead staining of mammalian cells - 100 tests.

Supplier: STEMCELL Technologies

Amphiregulin is a member of the epidermal growth factor (EGF) family. It binds to several receptors including EGFR/ErbB1, HER2/ErbB2, HER3/ErbB3, and HER4/ErbB4, which activates Ras/Raf/MAPK and PI3K/AKT pathways. This results in cell proliferation, apoptosis resistance, and invasive behaviour (Normanno et al.). The expression of amphiregulin is induced by tissue injury and inflammation. Amphiregulin promotes mammary development, trophoblast growth, lung and kidney branching morphogenesis, and keratinocyte proliferation. It stimulates the growth of most cell types, including normal and transformed mammary epithelial cells, and malignant cells of the colon, prostate, cervix, and pancreas (Berasain and Avila).

Supplier: STEMCELL Technologies

TRAIL (TNF-related apoptosis-inducing ligand) belongs to the tumor necrosis factor (TNF) superfamily and is associated with initiating apoptosis. TRAIL has four major receptors: two death receptors DR4 and DR5, and two decoy receptors DcR1 and DcR2. TRAIL binds to the death receptors, which recruits the Fas-associated death domain (FADD) and activates caspases 8 and 10, which eventually leads to apoptosis (Pitti et al.; Wiley et al.; Zauli and Secchiero). It has been shown that mice lacking the expression of TRAIL have defects in thymocyte apoptosis and negative selection, and these mice had increased susceptibility to autoimmune diseases (Lamhamedi-Cherradi et al.).

Supplier: STEMCELL Technologies

Cell culture medium for establishment and maintenance of mouse pancreatic exocrine organoids.

Supplier: STEMCELL Technologies

Immunomagnetic isolation of untouched human naïve CD4+ T cells.

Supplier: STEMCELL Technologies

Serum-free medium kit for highly efficient SMAD inhibition-mediated neural induction of human ES and iPS cells.

Supplier: STEMCELL Technologies

Defined cell culture medium for expansion of reset naïve human embryonic stem (ES) and induced pluripotent stem (iPS) cells.

Supplier: STEMCELL Technologies

Defined medium kit for transgene-free induction of reset naïve human pluripotent stem cells - 1 Kit