128743 Results for: "Biotin-PEG4-acid&"
Anti-GDNF Chicken Polyclonal Antibody
Supplier: Biosensis
GDNF is a glycosylated, disulfide-bonded homodimer molecule. It was first discovered as a potent survival factor for midbrain dopaminergic neurons and was then shown to rescue these neurons in animal models of Parkinson's disease. GDNF is about 100 times more efficient survival factor for spinal motor neurons than the neurotrophins. FUNCTION: Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake. SUBUNIT: Homodimer; disulfide-linked. SUBCELLULAR LOCATION: Secreted protein. ALTERNATIVE PRODUCTS: 2 named isoforms produced by alternative splicing. DISEASE: Defects in GDNF may be a cause of Hirschsprung disease (HSCR). In association with mutations of RET gene, defects in GDNF may be involved in Hirschsprung disease. This genetic disorder of neural crest development is characterized by the absence of intramural ganglion cells in the hindgut, often resulting in intestinal obstruction. DISEASE: Defects in GDNF are a cause of congenital central hypoventilation syndrome (CCHS); also known as congenital failure of autonomic control or Ondine curse. CCHS is a rare disorder characterized by abnormal control of respiration in the absence of neuromuscular or lung disease, or an identifiable brain stem lesion. A deficiency in autonomic control of respiration results in inadequate or negligible ventilatory and arousal responses to hypercapnia and hypoxemia. SIMILARITY: Belongs to the TGF-beta family. GDNF subfamily.
Expand 1 Items
Spectrophotometric colorimeters, PFXi 995 series, Lovibond®
Supplier: Lovibond Tintometer
The PFXi 995 spectrophotometers are top of the range, versatile instruments that offer comprehensive colour data requirements for either the Petrochemicals industry or the Food and Chemicals industries for edible oils, fats, chemicals etc. The PFXi 995 and PFXi 995/P provide objective, unbiased colour data according to a comprehensive range of established industry scales, spectral data and CIE values. They are ideal for companies that process a broad selection of product types with varied colour specifications, particularly in central test facilities or in independent testing laboratories. The instruments are easily customised to display only those scales of interest to the user.
Expand 4 Items
Anti-BDNF Mouse Monoclonal Antibody [clone: 4C8]
Supplier: Biosensis
BDNF belongs to the neurotrophin family and promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it. It is a major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability. The alterations in BDNF expression induced by various kinds of brain insult including stress, ischemia, seizure activity and hypoglycemia, may contribute to some pathologies such as depression, epilepsy, Alzheimer's, and Parkinson's disease. Microglia release BDNF that may contribute to neuroinflammation and neuropathic pain. SUBUNIT: Monomers and homodimers. Binds to NTRK2/TRKB. SUBCELLULAR LOCATION: Secreted protein. POst translation modification: Converted into mature BDNF by plasmin (PLG). SIMILARITY: Belongs to the NGF-beta family.
Expand 1 Items
Fibre analyser, FIWE advance automatic
Supplier: VELP SCIENTIFIC
The FIWE Advance is a fully automatic analyser for Crude and Detergent Fibre determination according to official reference methods. State of the art technology ensures safety, premium remote connectivity and a unique user experience. FIWE Advance Load and Go operation, requires minimum operator time, just 2 minutes, to improve productivity.
Expand 1 Items
Reactor systems, EasySyn
Supplier: IKA
EasySyn is the reactor system for organic or aqueous syntheses, and the only reactor system for which you can get all the complementary components from a single source: Overhead stirrers, circulators, vacuum pumps and controllers, sensors and automation software. All from IKA and all perfectly matched to each other. With its double-walled reactor vessels from 500 to 5000 ml, EasySyn is a medium-sized and very flexible upscaling system. It ensures safe and reproducible chemical reactions.
Expand 8 Items
Orion Star™ T910 pH Titrators
Supplier: Thermo Orion
The Thermo Scientific™ Orion Star™ T910 pH titrators are designed to increase your laboratory productivity by automating titrations. Our core electrochemistry technology is integrated with a state-of-the-art reagent dispensing system to create modern, simplified automated titrators designed to make performing titrations easier, more reliable and more reproducible than manual titrations.
Expand 3 Items
Laboratory and glassware washers, PG 8535 and PG 8536
Supplier: MIELE
These cleaning and disinfection machines with integrated drying system and drawer have been designed for the treatment of clinical instruments and for washing laboratory glassware in research laboratories, biology and pharmaceutical industries. The new PG 85 range offers a wide range of innovations such as freely programmable PROFITRONIC+ controls, PerfectSpeed spray arm monitoring, temperature independent PerfectFlow dispensing control on the basis of ultrasound as well as PerfectPureSensor conductivity metering.
Expand 3 Items
Microplate readers, Varioskan™ LUX
Supplier: THERMO LABSYSTEMS LIFE SCIENCE
Varioskan™ LUX comes equipped with a range of measurement technologies including absorbance, fluorescence intensity and FRET as standard, and with optional luminescence, AlphaScreen and time-resolved fluorescence (TRF) modules. The instrument selects the measurement wavelength using filters or monochromators, depending on which is optimal for each measurement technology.
Expand 15 Items
Zirconyl chloride octahydrate ≥98%
Supplier: Thermo Fisher Scientific
Zirconyl chloride octahydrate ≥98%
Expand 3 Items
L(+)-Histidine monohydrochloride monohydrate cell culture reagent
Supplier: Thermo Fisher Scientific
L(+)-Histidine monohydrochloride monohydrate cell culture reagent
Expand 3 Items
Human MAS1L ELISA kit
Supplier: ANTIBODIES.COM
Human MAS1L ELISA Kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of human MAS1L in serum, plasma, tissue homogenates, and other biological fluids.
Expand 1 Items
Mouse Apolipoprotein CIII ELISA kit
Supplier: ANTIBODIES.COM
Mouse Apolipoprotein CIII ELISA Kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of mouse Apolipoprotein CIII in serum, plasma, tissue homogenates, and other biological fluids.
Expand 1 Items
CHO Host Cell Proteins ELISA kit
Supplier: ANTIBODIES.COM
CHO Host Cell Proteins ELISA Kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of CHO Host Cell Proteins in serum, plasma, tissue homogenates, and other biological fluids.