Order Entry
Ireland
ContactUsLinkComponent
 

50835 Results for: "Alsto"

Corrected to: also

Stereo Microscope, Mantis ERGO

Supplier: VISION ENGINEERING

ERGO eyepiece-less optical stereo microscope with dynamic view optics.

Expand 2 Items
Loading...
DNA purification kits, Geneclean® kit, MP Biomedicals

DNA purification kits, Geneclean® kit, MP Biomedicals

Supplier: MP Biomedicals

The GeneClean® Kit is designed to purify fragments of DNA from 200 bp to 20 kb from solutions and agarose gels.

Expand 1 Items
Loading...
Cooled incubators, Series 1A

Cooled incubators, Series 1A

Supplier: LMS

LMS Series 1A cooled incubators are temperature controlled cabinets with fan assisted air circulation via a pre-mixing chamber. The units have a white enamelled sheet steel exterior, white pre-coated aluminium interior and polyurethane foam insulation, and feature a door lock and magnetic door gasket. The inner chamber is easy to clean, disinfection procedures are detailed in the user manual.

Expand 12 Items
Loading...
Cooled Incubators, Series 2

Cooled Incubators, Series 2

Supplier: LMS

LMS Series 2 cooled incubators are temperature controlled cabinets with fan assisted air circulation via a pre-mixing chamber. The units have a white enamelled sheet steel exterior, high impact plastic interior and polyurethane foam insulation, and feature a door lock and magnetic door gasket. The corrosion resistant inner chamber is easy to clean, disinfection procedures are detailed in the user manual.

Expand 12 Items
Loading...
RNA purification kit, Tri-Xtract™

RNA purification kit, Tri-Xtract™

Supplier: G-Biosciences

Tri-Xtract™ is designed for the isolation of total RNA that is free from protein and DNA contamination. The isolated RNA is suitable for Northern blots, dot blot hybridisation, in vitro translation, RNase protection assays and poly (A+) selection.

Expand 2 Items
Loading...
Biological upright microscopes, fixed Koehler LED, BA 210 LED

Biological upright microscopes, fixed Koehler LED, BA 210 LED

Supplier: MOTIC

Microscopes for basic work in biology life science. Fixed Koehler set-up gives adequate power resources for upgrading the microscope with contrast methods like phase contrast, polarisation or darkfield. The Motic BA 210 is a robust, ready to use with pre-installed set-up of optics and 3 W LED illumination.

Expand 5 Items
Loading...
Anti-Lamin A/C Chicken Polyclonal Antibody

Anti-Lamin A/C Chicken Polyclonal Antibody

Supplier: Biosensis

The Lamin proteins are members of the intermediate filament protein family but are located inside the nucleus rather than in the cytoplasm (1). The lamins function as skeletal components tightly associated with the inner nuclear membrane. Originally the proteins of the nuclear cytoskeleton were named Lamin A, B and C, from top to bottom as visualized on SDS-PAGE gels. Subsequently it was found that Lamins A and C were coded for by a single gene (2), while the Lamin B band may contain two proteins encoded by two genes now called Lamin B1 and Lamin B2. Lamin A has a mass of about 74kDa while Lamin C is 65kDa. The Lamin A protein includes 98 amino acids missing from Lamin C, while Lamin C has a C-terminal 6 amino acid peptide not present in Lamin A. Apart from these regions Lamin A and C are identical so that antibodies raised against either protein are likely to cross react with the other, as is the case with this monoclonal. Lamin polymerization and depolymerization is regulated by phosphorylation by cyclin dependent protein kinase 1 (CDK1), the key component of "maturation promoting factor", the central regulator of cell division. Activity of this kinase increases during cell division and is responsible for the breakdown of the nuclear lamina. Mutations in the LMNA gene are associated with several serious human diseases, including Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease type 2B1, and Hutchinson-Gilford progeria syndrome. This family of diseases belong to a larger group which are often referred to as Laminopathies, though some laminopathies are associated in defects in Lamin B1, B2 or one or other of the numerous nuclear lamina binding proteins. A truncated version of lamin A, commonly known as progerin, causes Hutchinson-Gilford progeria syndrome, a form of premature aging (3).

Expand 1 Items
Loading...
MicroSpin™ DNA Clean-up, Columns

MicroSpin™ DNA Clean-up, Columns

Supplier: Cytiva

MicroSpin™ columns are designed for the rapid purification of DNA in conjunction with Sephadex™ G-25 DNA grade for use in a wide range of applications, including desalting, buffer exchange and removal of unincorporated nucleotides from end-labelled oligonucleotides.

Expand 1 Items
Loading...
Sera-Xtracta Cell-Free DNA Kit

Sera-Xtracta Cell-Free DNA Kit

Supplier: Cytiva

Sera-Xtracta Cell-Free DNA Kit for the efficient extraction and purification of cell-free DNA (cfDNA) from plasma.

Expand 1 Items
Loading...
SPINeasy® DNA Kit for Blood, MP Biomedicals

SPINeasy® DNA Kit for Blood, MP Biomedicals

Supplier: MP Biomedicals

SPINeasy DNA kit for blood is a high-performance genomic DNA (gDNA) extraction kit based on silica-membrane spin-column technology. This kit enables quick isolation of gDNA from whole blood preserved in different anticoagulants (EDTA, Heparin and sodium citrate), typically in less than 30 minutes.

Expand 1 Items
Loading...
MagBeads FastDNA™ Kit for Feces

MagBeads FastDNA™ Kit for Feces

Supplier: MP Biomedicals

The MagBeads FastDNA Kit for Feces allows thorough sample lysis and quick isolation of DNA from fecal samples. It is using magnetic beads with high DNA binding capacity for extraction of high yields of pure DNA. This is done manually using a magnetic rack or adapted to automated instruments for high throughput processing.

Expand 1 Items
Loading...
Chemistry vacuum pumps and systems, MD 4C NT

Chemistry vacuum pumps and systems, MD 4C NT

Supplier: VACUUBRAND

These chemistry vacuum systems can be used in a wide range of applications for evacuating or moving gases and vapours between containers in chemistry and physics laboratories, e.g. as an alternative to water jet pumps and rotary vane pumps. Compact construction, very quiet running, long service life; diaphragm and valves are very easy to replace. Oil-free vacuum.

Expand 5 Items
Loading...

Testo 160 THL WiFi Data Logger with Integrated Sensors for Temperature, Humidity, LUX and UV Radiation

Supplier: TESTO

The testo 160 THL climate logger with integrated temperature, humidity, lux and UV sensors ensures comprehensive monitoring of the ambient climate and light conditions in museums at all times. The testo 160 THL belongs to the testo 160 data logger range, which was developed especially for the particular requirements in museums. Versatile options for combinations of integrated sensors and probes, any monitoring situation, from exhibitions to storage, is covered.

Expand 1 Items
Loading...
Anti-Amyloid beta-peptide Mouse Monoclonal Antibody [clone: MOAB-2]

Anti-Amyloid beta-peptide Mouse Monoclonal Antibody [clone: MOAB-2]

Supplier: Biosensis

The amyloid beta peptide is derived from the cleavage of the Amyloid precursor protein (APP) and varies in length from 39 to 43 amino acids. However, the form(s) of amyloid-beta peptide (Aβ) associated with the pathology characteristic of Alzheimer’s disease (AD) remains unclear. In particular, the neurotoxicity of intraneuronal Aβ accumulation is an area of considerable research and controversy principally because antibodies thought to be specific for Aβ have been shown to actually detect intraneuronal APP and not Aβ exclusively. MOAB-2 (mouse IgG2b) is a pan-specific, high-titer antibody to Aβ residues 1-4 as demonstrated by biochemical and immunohistochemical analyses (IHC), and is highly specific just to amyloid beta peptide. MOAB-2 did not detect APP or APP-CTFs in cell culture media/lysates (HEK-APPSwe or HEK APPSwe/BACE1) or in brain homogenates from transgenic mice expressing 5 familial AD (FAD) mutation (5xFAD mice). Using IHC on 5xFAD brain tissue, MOAB-2 immunoreactivity co-localized with C-terminal antibodies specific for Aβ40 and Aβ42. MOAB-2 did not co-localize with either N- or C-terminal antibodies to APP. In addition, no MOAB-2-immunreactivity was observed in the brains of 5xFAD/BACE-/- mice, although significant amounts of APP were detected by N- and C-terminal antibodies to APP, as well as by 6E10. In both 5xFAD and 3xTg mouse brain tissue, MOAB-2 co-localized with cathepsin-D, a marker for acidic organelles, further evidence for intraneuronal Aβ, distinct from Aβ associated with the cell membrane. MOAB-2 demonstrated strong intraneuronal and extra-cellular immunoreactivity in 5xFAD and 3xTg mouse brain tissues.

Expand 1 Items
Loading...
DNA isolation, Genomic DNA isolation kits, XIT™

DNA isolation, Genomic DNA isolation kits, XIT™

Supplier: G-Biosciences

G-Biosciences offers a wide selection of genomic isolation kits that purify high quality genomic DNA from a variety of sources and for a wide array of applications. G-Biosciences XIT™ DNA kits produce protein-free, high quality DNA through the principle of cell lysis, protein digestion and precipitation and genomic DNA purification. No chloroform or phenol extraction is required. High quality DNA can be isolated from sample types including: animal tissues, cells, whole blood, bacteria, buccal cells, plant tissues, mouse tail, yeast and FFPE tissue. G-Biosciences XIT™ DNA kit procedures remove contaminants and enzyme inhibitors allowing the purified DNA to be ready for immediate use for all downstream analyses. The purified DNA from G-Biosciences XIT™ DNA kits have a A₂₆₀/A₂₈₀ ratio between 1,7 and 1,9 (with the exception of the buccal cells kit with a ratio between 1,8 and 2,0) and are up to 200 kb in size.

Expand 23 Items
Loading...
Recommended for You