TOYOPEARL® Super A resin provides a cutting-edge experience in protein A media, blending top-tier critical performance attributes with exceptional operational flexibility. An efficient and durable protein A resin.

• State-of-the-art operational flexibility

  Supports high titers with high dynamic binding capacity (DBC)

  Enhanced alkaline stability for rigorous CIP

  Excellent pressure flow behavior to increase process efficiency

  Superior critical process performance

  Features mild elution conditions

  Reduction in process impurities, makes process robust, safe, and compliant

An enhanced, animal-origin free, recombinant protein A ligand is bound to the polymethacrylate base bead via multipoint attachment resulting in excellent base stability for up to 100 CIP cycles with 0,5 mol/L NaOH and up to 70 CIP cycles with 1 mol/L NaOH while maintaining 90% of its initial DBC.

TOYOPEARL Super A resin is available in ~45 µm particle size (F-grade) and exhibits dynamic binding capacities of greater than 70 g/L at 5 min residence time and greater than 60 g/L at 3 min residence time.

Improved mass transfer characteristics allow it to maintain a larger percent of its capacity at lower residence times relative to comparable agarose-based resins. It is therefore ideally suited for continuous operation using multiple short columns.

This resin is also available in pre-packed Skill Pak columns to simplify your process development and scale-up.

Bacterial count: max 100 CFU/ml

Endotoxin concentration: max 10 EU/ml

Delivery conditions: 72% slurry in 20% ethanol