Maturation kit for generation of functional neurons from human ES and iPS cell-derived neuronal precursor cells.

The STEMdiff™ Forebrain Neuron Maturation Kit is used in conjunction with the STEMdiff™ Forebrain Neuron Differentiation Kit to generate a mixed population of forebrain-type (FOXG1-positive) neurons from neural progenitor cells derived from human pluripotent stem cells. The neurons derived are highly pure (≥ 90% class III β-tubulin-positive neurons; <10% GFAP-positive astrocytes), functional and can be maintained long-term in culture. Neurons derived using these products are versatile tools for modeling human neurological development and disease, drug screening, toxicity testing, and cell therapy validation.