cGMP, human T cell activation and expansion reagent.

Achieve robust activation and expansion of human T cells for use in clinical applications - without the use of magnetic beads, feeder cells, or antigens. This products gentle activation stimulus ensures a high viability of activated T cells, which can be further expanded in ImmunoCult™-XF, a high-performance T cell expansion medium manufactured under relevant cGMP regulations and guidelines. ImmunoCult™ Human CD3/CD28/CD2 T cell activator consists of soluble antibody complexes that bind to and cross-link CD3, CD28, and CD2 cell surface ligands, providing the required primary and co-stimulatory signals for T cell culture and activation. ImmunoCult™ human CD3/CD28/CD2 T cell activator is designed for cell therapy clinical research applications, qualified for use as an ancillary material (AM) following the framework outlined in USP 1043 and/or PH. EUR. 5.2.12. STEMCELL can work with you to qualify this reagent as an AM under an approved Investigational New Drug (IND) application, Biological Licensing Application (BLA), or Clinical Trial Application (CTA).