Specifications
- Antibody type:Primary
- Antigen name:Protocadherin gamma-C3
- Antigen symbol:PCDHGC3
- Clonality:Polyclonal
- Conjugation:Unconjugated
- Flow cytometry:Yes
- Host:Rabbit
- ImmunoChemistry:Yes
- Reactivity:Human
- Western blot:Yes
- Epitope:Amino Acid Range = 511 - 539
- Form:Liquid
- Gene ID:Q9UN70
- Antigen synonyms:PCDHGC3
- Modification:None
- Storage buffer:Supplied in PBS with 0,09% (W/V) sodium azide.
- Molecular weight:101 kDa
- Storage temperature:Store at 4 °C for three months and –20 °C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Concentration:0,5 mg/ml
- Shipping temperature:4 °C
- Immunogen:This PCDHGC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 511 - 539 amino acids from the Central region of human PCDHGC3
- Purification:This antibody is purified through a protein A column, followed by peptide affinity purification.
- Pk:400 µl
Specifications
About this item
This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.
For WB starting dilution is: 1:1000. For IHC-P starting dilution is: 1:50~100. For FACS starting dilution is: 1:10~50.
Type: Primary
Antigen: PCDHGC3
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope: Amino Acid Range = 511-539
Host: Rabbit
Isotype:
Reactivity: Human