- Antibody type:Primary
- Antigen name:KCNQ2
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 680
- Flow cytometry:Yes
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Reactivity:Rat
- Epitope:91-150/872
- Form:Liquid
- Antigen synonyms:KCNQ2_HUMAN|Neuroblastoma specic potassium channel subunit alpha KvLQT2|Neuroblastoma-specic potassium channel subunit alpha KvLQT2|KCNQ 2|HNSPC|BFNC|KCNA 11|KQT like 2|KvLQT2|EBN|KVEBN 1|EIEE7|Potassium voltage gated channel KQT like protein 2|KCNA11|Potassium voltage gated channel KQT like subfamily member 2|Voltage-gated potassium channel subunit Kv7.2|EBN1|BFNS1|ENB1|Potassium voltage gated channel subfamily KQT member 2|Potassium voltage-gated channel subfamily KQT member 2|KvLQT 2|Neuroblastoma specic potassium channel protein|Neuroblastoma specic potassium channel alpha subunit KvLQT2|KVEBN1|KQT-like 2|Voltage gated potassium channel subunit Kv7.2|ENB 1|EBN 1|Kcnq2|KV7.2|Neuroblastoma specic potassium channel subunit alpha
- Modification:Unmodified
- Storage buffer:Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
- Molecular weight:96 kDa
- Storage temperature:Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentration:1 µg/µl
- Shipping temperature:4 °C
- Immunogen:KLH conjugated synthetic peptide derived from human KCNQ2
- Tested applications:ICC
- Purification:Purified by Protein A
- Pack type:Vial
- Pk:100 µl
Epilepsy affects about 0.5% of the world's population and has a large genetic component. Epilepsy results from an electrical hyperexcitability in the central nervous system. Potassium channels are important regulators of electrical Signalling, determining the firing properties and responsiveness of a variety of neurons. Benign familial neonatal convulsions (BFNC), an autosomal dominant epilepsy of infancy, has been shown to be caused by mutations in the KCNQ2 or the KCNQ3 potassium channel genes. KCNQ2 and KCNQ3 are voltage-gated potassium channel proteins with six putative transmembrane domains. Both proteins display a broad distribution within the brain, with expression patterns that largely overlap.
Type: Primary
Antigen: KCNQ2
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 680
Public Immunogen Range: 91-150/872
Host: Rabbit
Isotype: IgG
Reactivity: Rat