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Anti-FAK Ser732 Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Anti-FAK Ser732 Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Catalog # BOSSBS-1642R-A750
Supplier:  Bioss
Anti-FAK Ser732 Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Catalog # BOSSBS-1642R-A750
Supplier:  Bioss

Specifications

  • Antibody type:
    Primary
  • Antigen name:
    FAK Ser732
  • Clonality:
    Polyclonal
  • Conjugation:
    Alexa Fluor® 750
  • Flow cytometry:
    Yes
  • Host:
    Rabbit
  • ImmunoChemistry:
    Yes
  • ImmunoFluorescence:
    Yes
  • Isotype:
    IgG
  • Reactivity:
    Human,
    Mouse
  • Western blot:
    Yes
  • Form:
    Liquid
  • Gene ID:
    5747
  • Antigen synonyms:
    Focal adhesion kinase 1|pp125FAK|FAK1|PTK 2|p-FAK phospho S732|Protein phosphatase 1 regulatory subunit 71|p125FAK|PPP1R71|FAK1_HUMAN|FRNK|FADK|Focal adhesion kinase-related nonkinase|FAK phospho S732|Protein-tyrosine kinase 2|Protein tyrosine kinase 2|Protein Tyrosine Kinase Cytoplasmic|FAK related non kinase polypeptide|FAK 1|FADK 1
  • Modification:
    Phosphorylation (Ser732)
  • Storage buffer:
    Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
  • Molecular weight:
    116 kDa
  • Storage temperature:
    Store at –20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
  • Concentration:
    1 µg/µl
  • Shipping temperature:
    4 °C
  • Immunogen:
    KLH conjugated synthetic phosphopeptide derived from human FAK around the phosphorylation site of Tyr732
  • Tested applications:
    ICC
  • Purification:
    Purified by Protein A
  • Pack type:
    Vial
  • Pk:
    100 µl

Specifications

About this item

Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility, proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. Plays a potential role in oncogenic transformations resulting in increased kinase activity. [SUBCELLULAR LOCATION] Cell junction, focal adhesion. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Constituent of focal adhesions.

Type: Primary
Antigen: FAK Ser732
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse