Specifications
- Antibody type:Primary
- Antigen name:FAK Ser732
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 750
- Flow cytometry:Yes
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Reactivity:Human,Mouse
- Western blot:Yes
- Form:Liquid
- Gene ID:5747
- Antigen synonyms:Focal adhesion kinase 1|pp125FAK|FAK1|PTK 2|p-FAK phospho S732|Protein phosphatase 1 regulatory subunit 71|p125FAK|PPP1R71|FAK1_HUMAN|FRNK|FADK|Focal adhesion kinase-related nonkinase|FAK phospho S732|Protein-tyrosine kinase 2|Protein tyrosine kinase 2|Protein Tyrosine Kinase Cytoplasmic|FAK related non kinase polypeptide|FAK 1|FADK 1
- Modification:Phosphorylation (Ser732)
- Storage buffer:Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
- Molecular weight:116 kDa
- Storage temperature:Store at –20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentration:1 µg/µl
- Shipping temperature:4 °C
- Immunogen:KLH conjugated synthetic phosphopeptide derived from human FAK around the phosphorylation site of Tyr732
- Tested applications:ICC
- Purification:Purified by Protein A
- Pack type:Vial
- Pk:100 µl
Specifications
About this item
Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility, proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. Plays a potential role in oncogenic transformations resulting in increased kinase activity. [SUBCELLULAR LOCATION] Cell junction, focal adhesion. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Constituent of focal adhesions.
Type: Primary
Antigen: FAK Ser732
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse