Drometrizole trisiloxane (DRT) belongs to the lipophilic benzotriazole derivative class of compounds which is commonly utilised in sunscreen cosmetics.

Determined in active pharmaceutical ingredients (APIs), formulations and stability samples by reversed phase ultra-high performance liquid chromatography (RP-UPLC) coupled to electrospray ionization-quadrupole time-of-flight tandem mass spectrometry (ESI-QTOF-MS/MS), Suncare formulations by high performance liquid chromatography (HPLC) with ultraviolet (UV) detection, Cosmetic products by LC-UV and sewage sludge samples by QuEChERS extraction and gas chromatography combined with MS/MS.