Vitamin B12 (cyanocobalamin) 96.0-102.0% (dried basis) USP, Ph. Eur., BP pH 6.0 (1 g/l, H₂O, 20 °C), SAFC®
Supplier: MERCK PRODUCTION CHEMICALS
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About this item
CAS Number:68-19-9
:
Formula:C₆₃H₈₈CoN₁₄O₁₄P
MDL Number:MFCD00151092
:1355.38 g/mol
Merck Index:12,10152
Melting Pt:>300 °C
Storage Temperature:Refrigerator
EINECS:200-680-0
Specifications
- Environmentally Preferable:
Specifications
Specification Test Results
- Assay (Ph Eur, calculated on dried substance):96.0 - 102.0 %
- Assay (USP, calculated on dried substance):96.0 - 102.0 %
- Identity (IR-spectrum):passes test
- Identity (Cobalt):passes test
- Identity (HPLC):passes test
- Appearance:dark-red, crystalline powder or dark-red crystals
- Absorption ratio (A 361 nm/278 nm):1.70 - 1.90
- Absorption ratio (A 361 nm/550 nm):3.15 - 3.40
- As (Arsenic):≤ 3 ppm
- Cu (Copper):≤ 25 ppm
- Pb (Lead):≤ 10 ppm
- Zn (Zinc):≤ 25 ppm
- Related substances (HPLC, Ph Eur):≤ 3 %
- Related substances (HPLC, USP, 7ß,8ß-Lactocyanocobalamin):≤ 1.0 %
- Related substances (HPLC, USP, 50-Carboxycyanocobalamin):≤ 0.5 %
- Related substances (HPLC, USP, 34-Methylcyanocobalamin):≤ 2.0 %
- Related substances (HPLC, USP, 32-Carboxycyanocobalamin):≤ 1.0 %
- Related substances (HPLC, USP, 8-Epi-cyanocobalamin):≤ 1.0 %
- Related substances (HPLC, USP, Any other unidentified impurity):≤ 0.5 %
- Related substances (HPLC, USP, Total impurities):≤ 3.0 %
- Acetone (HS-GC):≤ 5000 ppm
- Other residual solvents (ICH Q3C):excluded by production process
- Loss on drying (Ph Eur):≤ 12.0 %
- Loss on drying (USP):≤ 12.0 %
Specification Test Results
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