G-type-iODN
ENZOALX746252C100
:
- Pk:100 µG
- Seq:02
- Reconstitution instructions:For a 100 µM stock solution, dissolve the total vial content in 150 µl endotoxin-free water (included) or PBS (to order separately). To obtain optimal dissolving we recommend the following procedure:
- Add 50% of the solvent and let dissolve for 10 min. - Endotoxin-free:Yes
- Protein/peptide name:G-type-iODN
- Formulation:Lyophilised. Sterile.
TLR9 inhibitor
Inhibitory iODN oligodeoxynucleotide with phosphorothioate backbone. Potent sequence of an inhibitory ODN based on poly-G class I sequences targeting TLR9, but without additional effect on TLR7 and TLR8 signaling, for in vivo use in rodents (50-150 µg per injection). For active CpG compounds see e.g. ODN 1668 (Prod. No. ALX-746-001).
Synthetic.
: Quantity: ~15 nmol (100 µg). Sufficient for ~100 cellular inhibition assays. Working concentration depends upon concentration, type and MW of stimulating CpG ODN, the cellular system and read-out used. Titrate at 3-5 fold molar excess for inhibition.