Human recombinant Cathepsin K
Catalog # ENZOBMLSE5530010
Supplier: ENZO LIFE SCIENCES
CAS Number:
Specifications
- Pk:10 µG
- Protein/peptide type:Recombinant
- Species:Human
- Seq:02
- Protein/peptide name:Cathepsin K
- Purity:>95% (SDS-PAGE)
- Concentration:0,023 mg/ml
- Formulation:Liquid. In 50 mM sodium acetate, pH 5,5, containing 50 mM sodium chloride, 0,5 mM EDTA and 5 mM DTT.
Specifications
About this item
Highly active
Produced in insect cells. Purified as full-length proenzyme (see Prod. No. BML-SE367), then auto-activated at low pH.
Cathepsin K, a member of the papain family of cysteine proteases, acts upon proteins such as collagen, AL amyloid, kinin, and elastin. It is a lysosomal protease expressed primarily in osteoclasts, but also in other cell types such as macrophages. It functions in bone remodeling and is implicated in disease states such as osteoporosis, atherosclerosis, arthritis, and pycnodysostosis.