Human recombinant RAP (from E. coli)
Catalog # ENZOBMLSE5520100
Supplier: ENZO LIFE SCIENCES
CAS Number:
Specifications
- Pk:100 µG
- Protein/peptide type:Recombinant
- Source:E. coli
- Species:Human
- Seq:02
- Protein/peptide name:RAP
- Purity:>90% (SDS-PAGE)
Specifications
About this item
Produced in E. coli.
RAP functions in ER maturation of lipoprotein receptor family members by acting as an antagonist. It blocks binding of PCSK9 to lipoprotein receptors and of all known ligands (including MMP-9 and apoE) to lipoprotein receptor-related protein 1 (LRP-1). Modulates amyloid deposition in mouse models of Alzheimer’s disease. Reduces endocytosis of prion protein (PrPc) by neuronal cells.