Human recombinant GDP-L-Fucose Synthase (from E. coli)
Catalog # PRSI91-969
Supplier: ProSci Inc.
CAS Number:
Specifications
- Pk:50 µG
- Enzyme type:Recombinant
- Source:E. coli
- Species:Human
- Tag sequence:C-6 His tag
- Storage conditions:Store at −20 °C, stable for 6 months after receipt. Please minimize freeze−thaw cycles.
- Enzyme name:GDP-L-Fucose Synthase
- Purity:>95% as determined by reducing SDS-PAGE
- Molecular weight:36.96 kD
- Sequence:Met1-Lys321
- Formulation:Supplied as a 0.2 µm filtered solution of 20 mM Tris, 150 mM NaCl, pH 8.0. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
- Tested applications:Bioassay
Specifications
About this item
GDP-L-Fucose Synthase is a NADP(H)-binding protein. It catalyses the two-step epimerase and the reductase reactions in GDP-D-mannose metabolism, converting GDP-4-keto-6-D-dexoymannose to GDP-L-fucose. GDP-L-Fucose is the substrate of several fucosyltransferase, involving the expression of mamy glycoconjugates, including blood group ABH antigens and development adhesion antigens. Mutations in the TSTA3 gene may cause leukocyte adhesion deficiency type II.
Fusion-Tag: C-6 His tag
This recombinant protein can be used for biological assays. For research use only.