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Human recombinant UBE2D1 (from E. coli)
Human recombinant UBE2D1 (from E. coli)
Catalog # PRSI92-272
Supplier:  ProSci Inc.
CAS Number:  
Human recombinant UBE2D1 (from E. coli)
Catalog # PRSI92-272
Supplier:  ProSci Inc.
CAS Number:  

Specifications

  • Pk:
    50 µG
  • Protein/peptide type:
    Recombinant
  • Source:
    E. coli
  • Species:
    Human
  • Tag sequence:
    N-GST tag
  • Storage conditions:
    Lyophilized protein should be stored at −20 °C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7 °C for 2-7 days. Aliquots of reconstituted samples are stable at −20 °C for 3 months.
  • Protein synonyms:
    Ubiquitin-conjugating enzyme E2(17)KB 1|Ubiquitin-protein ligase D1|UBCH5A|UBC4/5 homolog|Ubiquitin carrier protein D1|UbcH5|SFT|UBC5A|Ubiquitin-conjugating enzyme E2 D1|Stimulator of Fe transport|Ubiquitin-conjugating enzyme E2-17 kDa 1
  • Protein/peptide name:
    UBE2D1
  • Purity:
    > 95% as determined by reducing SDS-PAGE
  • Molecular weight:
    42.9 kD
  • Sequence:
    Met1-Met147
  • Formulation:
    Lyophilized from a 0.2 um filtered solution of 50mM HEPES,150mM NaCl,2mM DTT,10% Glycerin pH7.5. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the Lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
  • Tested applications:
    Bioassay

Specifications

About this item

Ubiquitin-conjugating enzyme E2 D1(UBE2D1)belongs to the ubiquitin-conjugating enzyme family. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This enzyme is closely related to a stimulator of iron transport (SFT), and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases.

Fusion-Tag: N-GST tag

This recombinant protein can be used for biological assays. For research use only.