Human Recombinant CD2001 (from HEK293 cells)
Catalog # PRSI96-573
Supplier: ProSci Inc.
CAS Number:
Specifications
- Pk:100 µG
- Protein/peptide type:Recombinant
- Source:HEK293 cells
- Species:Human
- Biological activity:Measured by its binding ability in a functional ELISA. Immobilized recombinant human CD200R1 at 2μg/ml,the concentration of rhCD200 that produces 50% of the optimal binding response is appoximately 0. 5‑16 ng/mL.
- Protein synonyms:OX-2|MOX1|My033|MRC|MOX2|CD200
- Protein/peptide name:CD2001
- Purity:>98% as determined by SDS-PAGE.
- Molecular weight:23.4 kDa
- Formulation:Lyophilized, PBS, pH7.4
- Tested applications:Western Blot
Specifications
About this item
CD200 is also known as OX-2 membrane glycoprotein (OX-2), is a type-1 membrane glycoprotein, which contains two immunoglobulin domains (1 Ig-like C2-type (immunoglobulin-like) domain and Ig-like V-type (immunoglobulin-like) domain), and thus belongs to the immunoglobulin superfamily. CD200 / OX-2 is widely expressed in multiple cell types. CD200 interacts with a structurally related receptor (CD200R) expressed mainly on myeloid cells and is involved in regulation of macrophage and mast cell function. OX-2 / CD200 and CD200R associate via their respective N-terminal Ig-like domains. CD200 also plays an important role in prevention of graft rejection, autoimmune diseases and spontaneous abortion.