The 2D1 antibody reacts with human CD45, one of the most abundant hematopoietic markers and one that is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). CD45 is a protein tyrosine phosphatase existing in several isoforms, each being generated and expressed in cell-specific patterns. With its broad cell distribution, CD45 is critical for many leukocyte functions, regulating signal transduction and cell activation associated with the T cell receptor, B cell receptor, and IL-2 receptor. Other forms of CD45, with restricted cellular expression, include CD45R (B220), CD45RA, CD45RB, and CD45RO. The 2D1 antibody is widely used as a marker for human CD45 expression on peripheral blood T cells, B cells, monocytes, macrophages, and NK cells.
Type: Primary
Antigen: CD45
Clonality: Monoclonal
Clone: 2D1
Conjugation: PE (Phycoerythrin)-Cyanine5
Epitope:
Host: Mouse
Isotype: Mouse IgG1, kappa
Reactivity: Human
- Catalog No:
- 55-9459-T100
- 55-9459-T025
- Antigen symbol:
- CD45
- CD45
- Antigen synonyms:
- Leukocyte Common Antigen, LCA, Ly-5, Hle-1
- Leukocyte Common Antigen, LCA, Ly-5, Hle-1
- Antibody type:
- Primary
- Primary
- Clonality:
- Monoclonal
- Monoclonal
- Conjugation:
- PE (Phycoerythrin)/Cy5®
- PE (Phycoerythrin)/Cy5®
- Clone:
- 2D1
- 2D1
- Reactivity:
- Human
- Human
- Host:
- Mouse
- Mouse
- Gene ID:
- 5788
- 5788
- Isotype:
- IgG1 kappa
- IgG1 kappa
- Flow cytometry:
- Yes
- Yes
- Storage temperature:
- 2-8°C protected from light
- 2-8°C protected from light
: VWR Collection
: VWR Collection
: VWR Chemicals
: VWR Chemicals
: VWR Collection
: VWR Collection
: VWR Collection
: KIMBERLY CLARK