This antibody reacts with a 75 kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi.Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.
Type: Primary
Antigen: TYRP1
Clonality: Monoclonal
Clone: TA99
Conjugation: CF488A
Epitope:
Host: Mouse
Isotype: IgG2a, kappa
Reactivity: Human, Mouse
- Catalog No:
- BNC880806-100
- BNC880806-500
- Antigen symbol:
- TYRP1
- TYRP1
- Antigen name:
- TRP1
- TRP1
- Antibody type:
- Primary
- Primary
- Clonality:
- Monoclonal
- Monoclonal
- Conjugation:
- CF® 488A
- CF® 488A
- Clone:
- Clone TA99
- Clone TA99
- Reactivity:
- Human, Mouse
- Human, Mouse
- Host:
- Mouse
- Mouse
- Gene ID:
- 270279
- 270279
- Isotype:
- IgG2a kappa
- IgG2a kappa
- ImmunoChemistry:
- Yes
- Yes
- ImmunoFluorescence:
- Yes
- Yes
- Concentration:
- 0,1 mg/ml
- 0,1 mg/ml
- Storage buffer:
- PBS/0,1% BSA/0,05% azide
- PBS/0,1% BSA/0,05% azide
: VWR Collection
: VWR Collection
: VWR Chemicals
: VWR Chemicals
: KIMBERLY CLARK
: VWR Collection
: VWR Collection
: VWR Collection