About this item
This antibody recognizes a transmembrane glycoprotein of 95 kDa, identified as CD18 or integrin -2 (Workshop III). It complexes non-covalently with either L, M, or X integrin (CD11a, b, or c) to form the heterodimers, LFA-1, Mac-1, and p150,95, respectively. LFA-1 is the receptor for three members of the Ig supergene family of proteins, ICAM-1 (CD54), ICAM-2 (CD102), and Mac-1 and p150,95 bind to ICAM-1, fibrinogen, and iC3b. ICAM-3 (CD50). CD18/CD11 heterodimeric molecules are involved with cell/cell and cell/extracellular adhesion in immune and inflammatory responses. This MAb blocks these cellular interactions.
Type: Primary
Antigen: ITGB2
Clonality: Monoclonal
Clone: 68-5A5
Conjugation: CF640R
Epitope:
Host: Mouse
Isotype: IgG2a kappa
Reactivity: Human
Specifications
- Catalog No:
- BNC400321-100
- BNC400321-500
- Antigen symbol:
- ITGB2
- ITGB2
- Antigen name:
- CD18
- CD18
- Antibody type:
- Primary
- Primary
- Clonality:
- Monoclonal
- Monoclonal
- Conjugation:
- CF® 640R
- CF® 640R
- Clone:
- Clone 68-5A5
- Clone 68-5A5
- Reactivity:
- Human
- Human
- Host:
- Mouse
- Mouse
- Gene ID:
- 375957
- 375957
- Isotype:
- IgG2a kappa
- IgG2a kappa
- ImmunoFluorescence:
- Yes
- Yes
- Concentration:
- 0,1 mg/ml
- 0,1 mg/ml
- Storage buffer:
- PBS/0,1% BSA/0,05% azide
- PBS/0,1% BSA/0,05% azide
Specifications
Supplier: VWR Chemicals
Supplier: HEATHROW
Supplier: VWR Collection
Supplier: Merck
Supplier: VWR Collection
Supplier: VWR Chemicals
Supplier: VWR Chemicals
Supplier: VWR Chemicals
Supplier: VWR Collection
Supplier: VWR Collection
Supplier: KIMBERLY CLARK
Supplier: VWR Collection