CD2 interacts through its amino-terminal domain with the extracellular domain of CD58 (also designated CD2 ligand) to mediate cell adhesion. CD2/CD58 binding can enhance antigen-specific T cell activation. CD2 is a transmembrane glycoprotein that is expressed on peripheral blood T lymphocytes, NK cells and thymocytes. CD58 is a heavily glycosylated protein with a broad tissue distribution in hematopoietic and other cells, including endothelium. Interaction between CD2 and its counter receptor LFA3 (CD58) on opposing cells optimizes immune system recognition, thereby facilitating communication between helper T lymphocytes and antigen-presenting cells, as well as between cytolytic effectors and target cells.
Type: Primary
Antigen: CD2
Clonality: Monoclonal
Clone: BH1
Conjugation: CF488A
Epitope:
Host: Mouse
Isotype: IgG2b kappa
Reactivity: Human
- Catalog No:
- BNC880320-100
- BNC880320-500
- Antigen symbol:
- CD2
- CD2
- Antigen name:
- CD2 molecule
- CD2 molecule
- Antigen synonyms:
- Rosette receptor|Erythrocyte receptor|Ly-37|T-cell surface antigen T11/Leu-5|T11|T-cell surface antigen CD2|SRBC|LFA-3 receptor|LFA-2|Lymphocyte function antigen 2
- Rosette receptor|Erythrocyte receptor|Ly-37|T-cell surface antigen T11/Leu-5|T11|T-cell surface antigen CD2|SRBC|LFA-3 receptor|LFA-2|Lymphocyte function antigen 2
- Antibody type:
- Primary
- Primary
- Clonality:
- Monoclonal
- Monoclonal
- Conjugation:
- CF® 488A
- CF® 488A
- Clone:
- Clone BH1
- Clone BH1
- Reactivity:
- Human
- Human
- Host:
- Mouse
- Mouse
- Gene ID:
- 523500
- 523500
- Isotype:
- IgG2b kappa
- IgG2b kappa
- ImmunoFluorescence:
- Yes
- Yes
- Concentration:
- 0,1 mg/ml
- 0,1 mg/ml
- Storage buffer:
- PBS/0,1% BSA/0,05% azide
- PBS/0,1% BSA/0,05% azide
: VWR Chemicals
: KIMBERLY CLARK
: VWR Collection
: VWR Chemicals
: VWR Collection
: VWR Collection
: VWR Collection
: VWR Collection