The EBVCS-5 antibody is specific for human CD23, also known as the low affinity IgE receptor (FceRII), a 45 kDa type II transmembrane protein and member of the immunoglobulin superfamily. It is expressed on most B cells and is upregulated upon activation. It is also present on mantle zone B cells, eosinophils, monocytes and a subset of T cells and platelets. CD23 plays a role in B cell development and differentiation, and also functions to regulate IgE production. Soluble secreted forms of CD23 have been reported to bind IgE, stimulate release of pro-inflammatory cytokines from monocytes, and play a role in B cell differentiation.
Type: Primary
Antigen: CD23
Clonality: Monoclonal
Clone: EBVCS-5
Conjugation: PE (Phycoerythrin)
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Human
- Catalog No:
- 50-0237-T100
- 50-0237-T025
- 50-0237-T500
- Antigen symbol:
- FCER2
- FCER2
- FCER2
- Antigen name:
- Fc fragment of IgE receptor 2
- Fc fragment of IgE receptor 2
- Fc fragment of IgE receptor 2
- Antigen synonyms:
- CLEC4J|BLAST-2|FCE2|CD23A|CD23|IGEBF
- CLEC4J|BLAST-2|FCE2|CD23A|CD23|IGEBF
- CLEC4J|BLAST-2|FCE2|CD23A|CD23|IGEBF
- Antibody type:
- Primary
- Primary
- Primary
- Clonality:
- Monoclonal
- Monoclonal
- Monoclonal
- Conjugation:
- PE (Phycoerythrin)
- PE (Phycoerythrin)
- PE (Phycoerythrin)
- Clone:
- EBVCS-5
- EBVCS-5
- EBVCS-5
- Reactivity:
- Human
- Human
- Human
- Host:
- Mouse
- Mouse
- Mouse
- Gene ID:
- 2208
- 2208
- 2208
- Isotype:
- IgG1 kappa
- IgG1 kappa
- IgG1 kappa
- Flow cytometry:
- Yes
- Yes
- Yes
- Cross adsorption:
- No
- No
- No
- Storage temperature:
- Store undiluted at 2-8 °C, protect from light, do not freeze.
- Store undiluted at 2-8 °C, protect from light, do not freeze.
- Store undiluted at 2-8 °C, protect from light, do not freeze.