- Antibody type:Primary
- Antigen name:Retinoid-Related Orphan Receptor Gamma
- Antigen symbol:RZRG
- Clonality:Monoclonal
- Clone:4G419
- Conjugation:Unconjugated
- Flow cytometry:Yes
- Host:Mouse
- Isotype:IgG1 kappa
- Reactivity:Primates,Human,Rat,Mouse
- Western blot:Yes
- Environmentally Preferable:
- Form:Liquid
- Gene ID:6097, 19885
- Antigen synonyms:RZRG|NR1F3|nuclear receptor ROR-gamma|RORG|retinoid-related orphan receptor gamma|RAR-related orphan nuclear receptor variant 2|RP11-98D18.11-001|RZR-GAMMA|nuclear receptor RZR-gamma|retinoic acid-binding receptor gamma|nuclear receptor subfamily 1 group F member 3|TOR
- Storage buffer:PBS, 0.05% BSA, 0.05% sodium azide
- Storage temperature:Store at 4 °C short term. For long term storage, store at –20 °C, avoiding freeze/thaw cycles.
- Concentration:0.5 mg/ml
- Shipping temperature:Ice
- Immunogen:Synthetic peptide (2 DRAPQRQHRASRELLAAKKTHTSQIE 27) of Retinoid-Related Orphan Receptor Gamma protein.
- Purification:Affinity chromatography
- Size:100 ug
- Pk:100 µG
ROR gamma is a 560 amino acid novel DNA-binding transcription factor belonging to the ROR/RZR orphan nuclear receptor subfamily. Reports suggest that ROR gamma is a ligand activated transcription factor and may be essential for lymphoid organogenesis (lymph nodes and Peyer's patches) and may play an important regulatory role in controlling apoptosis during thymopoiesis. ROR gamma inhibits the expression of Fas ligand and IL2 and directs the differentiation program of proinflammatory IL-17+ T helper cells. ROR gamma shares 50 to 51% sequence identity with RORA and RORB and is 88% identical to mouse ROR gamma. It is highly expressed in skeletal muscle and at lower levels in various other tissues.
Type: Primary
Antigen: RZRG
Clonality: Monoclonal
Clone: 4G419
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG1, kappa
Reactivity: Rat, Human, Primates, Mouse