Specifications
- Antibody type:Primary
- Antigen name:Oligodendrocyte Transcription Factor 2
- Antigen symbol:OLIG2
- Clonality:Monoclonal
- Clone:1G11
- Conjugation:Unconjugated
- Host:Mouse
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG1
- Reactivity:Human
- Western blot:Yes
- Format:ascites
- Form:Liquid
- Gene ID:10215
- Antigen synonyms:RACK17|basic domain|oligodendrocyte transcription factor 2|bHLHe19|class B|class B basic helix-loop-helix protein 1|PRKCBP2|BHLHB1|human protein kinase C-binding protein RACK17|1|class E basic helix-loop-helix protein 19|OLIGO2|helix-loop-helix protein|protein kinase C-binding protein 2|oligodendrocyte-specific bHLH transcription factor 2
- Storage buffer:ascites, 0.03% sodium azide
- Storage temperature:Store at 4 °C short term. For long term storage, store at –20 °C, avoiding freeze/thaw cycles.
- Shipping temperature:Ice
- Immunogen:Purified recombinant fragment of human OLIG2 expressed in E. Coli.
- Size:100 µL
- Pk:100 µl
Specifications
About this item
MA5-15810 targets OLIG2 in IF, IHC, and WB applications and shows reactivity with Human samples. The MA5-15810 immunogen is purified recombinant fragment of human OLIG2 expressed in E. Coli. MA5-15810 detects OLIG2 which has a predicted molecular weight of approximately 32kDa. This gene encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. The protein is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in a chromosomal translocation t(14;21)(q11.2;q22) associated with T-cell acute lymphoblastic leukemia. Its chromosomal location is within a region of chromosome 21 which has been suggested to play a role in learning deficits associated with Down syndrome. Tissue specificity: Expressed in the brain, in oligodendrocytes. Strongly expressed in oligodendrogliomas, while expression is weak to moderate in astrocytomas. Expression in glioblastomas highly variable.
Type: Primary
Antigen: OLIG2
Clonality: Monoclonal
Clone: 1G11
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Human