Specifications
- Antibody type:Primary
- Antigen name:Ataxia telangiectasia mutated
- Antigen symbol:ATM
- Clonality:Monoclonal
- Clone:2C1
- Conjugation:Unconjugated
- ELISA:Yes
- Flow cytometry:Yes
- Host:Mouse
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- ImmunoPrecipitation:Yes
- Isotype:IgG1
- Reactivity:Primates,Human,Rat,Mouse
- Western blot:Yes
- ChIP:Yes
- Form:Liquid
- Gene ID:300711, 11920, 472
- Antigen synonyms:AT complementation group D|AT mutated protein|Ataxia t|AT1|AT complementation group E|AT complementation group C|ATA|AT complementation group A
- Storage buffer:PBS, no preservative, pH 7.4
- Storage temperature:-20° C, Avoid Freeze/Thaw Cycles
- Concentration:1.85 mg/ml
- Shipping temperature:Ice
- Immunogen:Recombinant protein expressed in E. coli corresponding to amino acids 2577-3056.
- Purification:Protein G
- Size:100 µl
- Pk:100 µG
Specifications
About this item
MA1-23152 detects ATM in human, rat, mouse and monkey samples. MA1-23152 has been successfully used in ChIP Assay, ELISA, FACS, immunocytochemistry, immunofluorescence, immunohistochemistry (paraffin), immunoprecipitation and Western blot procedures. Predicted molecular weight of MA1-23152 is ~350kDa. MA1-23152 immunogen corresponds to recombinant protein expressed in E. coli corresponding to amino acids 2577-3056. ATM-2C1 recognizes full-length ATM, a 370kDa nuclear phosphoprotein, which is involved in the autosomal recessive disease ataxia telangiectasia (AT). ATM belongs to a novel family of proteins associated with cell cycle regulation and response to DNA repair. The C-terminal region has extensive homology to the catalytic domains of phosphatidylinositol 3-kinases (PI3 kinases). Its usefulness to monitor altered ATM expression in cancer is under active investigation.
Type: Primary
Antigen: ATM
Clonality: Monoclonal
Clone: 2C1
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Human, Primates, Rat, Mouse