The HI100 antibody reacts with the human CD45 isoform known as CD45RA, a protein tyrosine phosphatase of 220 kDa. CD45 is one of the most abundant hematopoietic markers, and is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). Various isoforms are generated and expressed in cell-specific patterns. With their broad cell distribution, CD45 isoforms are critical for many leukocyte functions, regulating signal transduction and cell activation associated with the T cell receptor, B cell receptor, and IL-2 receptor. Other forms of CD45, with restricted cellular expression, include CD45R (B220), CD45RB and CD45RO.
The HI100 antibody is widely used as a marker for human CD45RA expression on naïve and activated T cells, B cells, and monocytes.
Type: Primary
Antigen: CD45RA (CD45RA)
Clonality: monoclonal
Clone: HI100
Conjugation: PE (Phycoerythrin)/Cy7®
Epitope:
Host: Mouse
Isotype: IgG2b Kappa
Reactivity:
- Catalog No:
- 60-0458-T100
- 60-0458-T025
- Antigen symbol:
- PTPRC
- PTPRC
- Antigen name:
- Protein tyrosine phosphatase receptor type C
- Protein tyrosine phosphatase receptor type C
- Antigen synonyms:
- CD45R|B220|CD45|GP180|T200|L-CA|LY5|receptor type C|LCA|protein tyrosine phosphatase
- CD45R|B220|CD45|GP180|T200|L-CA|LY5|receptor type C|LCA|protein tyrosine phosphatase
- Antibody type:
- Primary
- Primary
- Clonality:
- Monoclonal
- Monoclonal
- Conjugation:
- PE (Phycoerythrin)/Cy7®
- PE (Phycoerythrin)/Cy7®
- Clone:
- HI100
- HI100
- Reactivity:
- Chimpanzee, Human
- Chimpanzee, Human
- Host:
- Mouse
- Mouse
- Gene ID:
- 5788
- 5788
- Isotype:
- IgG2b kappa
- IgG2b kappa
- Western blot:
- Yes
- Yes
- ImmunoChemistry:
- Yes
- Yes
- Flow cytometry:
- Yes
- Yes
- Cross adsorption:
- none
- none
- Storage temperature:
- Store undiluted at 2...8 °C, protect from light, do not freeze.
- Store undiluted at 2...8 °C, protect from light, do not freeze.
- Shipping temperature:
- Ice
- Ice
- Tested applications:
- Flow Cytometry
- Flow Cytometry
: VWR Chemicals
: KIMBERLY CLARK
: VWR Collection
: VWR Collection
: VWR Collection
: VWR Chemicals
: VWR Collection
: VWR Collection