Anti-JUN Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Catalog # BOSSBS-5463R-A555

Supplier: Bioss

Catalog # BOSSBS-5463R-A555

Supplier: Bioss

Specifications

Antibody type:
Primary
Antigen name:
c-Jun
Antigen symbol:
JUN
Clonality:
Polyclonal
Conjugation:
Alexa Fluor® 555
Host:
Rabbit
ImmunoChemistry:
Yes
Isotype:
IgG
Reactivity:
Human,
Rat,
Mouse
Cross adsorption:
No
Form:
liquid
Gene ID:
3725
Antigen synonyms:
Transcription factor AP-1|V-jun avian sarcoma virus 17 oncogene homolog|JUN|AP1|p39|Proto-oncogene c-jun|Activator protein 1
Modification:
phospho-Tyr170
Storage buffer:
Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Storage temperature:
Store at 4°C for 12 months
Concentration:
1 μg/μl
Shipping temperature:
4°C
Purification:
Purified by Protein A
Pk:
100 µl

Specifications

About this item

The human protooncogene JUN is the putative transforming gene of avian sarcoma virus 17, and it encodes a protein which is highly homologous to the viral protein. cJun (previously known as the Fos binding protein p39) and c Fos form a complex in the nucleus. AP 1 (activating protein 1) is a collective term referring to these dimeric transcription factors composed of Jun, Fos or ATF subunits that bind to a common DNA site, the AP1 binding site. AP 1 proteins, mostly the Jun group, regulate the expression and function of cell cycle regulators such as Cyclin D1, p53, p21 (cip1/waf1), p19 (ARF) and p16. Fos and Jun proto oncogene expression is induced transiently by a variety of extracellular stimuli associated with mitogenesis, differentiation processes or depolarization of neurons. JUN has been mapped to 1p32 to p31, a chromosomal region involved in both translocations and deletions in human malignancies.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: JUN
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 555
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat