Specifications
- Antibody type:Primary
- Antigen name:Factor 8 beta chain
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 750
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Reactivity:Human
- Western blot:Yes
- Epitope:1101-1200/2351
- Form:Liquid
- Gene ID:2157
- Antigen synonyms:coagulation factor VIII|OTTHUMP00000061446|Coagulation factor VIII isoform b|F8c|FA8_HUMAN|HEMA|FVIII|DXS1253E|FactorVIII|F8C|Procoagulant component|Coagulation factor VIII|F8|Hemophilia a|Coagulation factor VIIIc|Factor VIIIa heavy chain, 92 kDa isoform|Hemophilia classic|Coagulation factor VIII procoagulent component|Hema coagulation factor VIIIc procoagulent component|Coagulation factor VIII associated protein b|Factor VIII B chain|Factor VIII F8b|Ahf|Antihemophilic factor|Factor VIIIa heavy chain, 200 kDa isoform|Dna segment on chromosome x unique 1253 expressed sequence|AHF|F?-Ag|F8b|Dxs1253e|F8 protein|F8B
- Modification:Unmodified
- Storage buffer:Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
- Molecular weight:138 kDa
- Storage temperature:Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentration:1 µg/µl
- Shipping temperature:4 °C
- Immunogen:KLH conjugated synthetic peptide derived from human Factor VIII B chain
- Tested applications:ICC
- Purification:Purified by Protein A
- Pack type:Vial
- Pk:100 µl
Specifications
About this item
This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation; factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder.
Type: Primary
Antigen: Factor 8 beta chain
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range: 1101-1200/2351
Host: Rabbit
Isotype: IgG
Reactivity: Human