GammaBind™ Plus Sepharose™ is GammaBind G, type 3, covalently immobilised to Sepharose™ CL-6B by malimide linkage.

• For affinity chromatography
• Recombinant Protein G type 3 coupled to Sepharose CL-6B for enhanced binding to rat and mouse IgG subclasses at laboratory scale
• Binds to all IgG subclasses from human, mouse, and rat; binds total IgG from guinea pig, rabbit, goat, cow, sheep, and horse
• Maleimide activation coupling method
• Yields up to 18 mg/mL mouse IgG
• Stable in all commonly used aqueous buffers

GammaBind G, Type 3, a recombinant form of streptococcal protein G, binds to the Fc region of IgG from a variety of mammalian species. GammaBind Plus Sepharose may be used to analyze and purify classes, subclasses and fragments of immunoglobulins from any biological fluid or cell culture medium. Since only the Fc region is involved in binding, the Fab region is still available for binding antigen.