2429 Résultats pour : "STEMCELL Technologies"

Supplier: STEMCELL Technologies

Immunomagnetic isolation of untouched myeloid-derived suppressor cells (CD11b+Gr1+).

Supplier: STEMCELL Technologies

Immunomagnetic isolation of untouched human neutrophils.

Supplier: STEMCELL Technologies

Serum-free media for differentiation of human PSCs to cardiomyocytes and long-term maintenance of human PSC-derived cardiomyocytes.

Supplier: STEMCELL Technologies

Culture supplement for the differentiation of human naïve CD4+ T cells into tregs.

Supplier: STEMCELL Technologies

For the culture of mouse MSCs and MEFs.

Supplier: STEMCELL Technologies

Immunomagnetic positive selection of CD2+ cells.

Supplier: STEMCELL Technologies

Cell culture medium for further differentiation of human intestinal organoids in 3D, or as monolayers/air-liquid interface cultures.

Supplier: STEMCELL Technologies

Column-free immunomagnetic positive selection of human CD33+ cells for HLA analysis.

Supplier: STEMCELL Technologies

Cell culture supplement.

Supplier: STEMCELL Technologies

Immunomagnetic isolation of untouched mouse plasmacytoid dendritic cells (pDC)

Supplier: STEMCELL Technologies

cGMP, enzyme-free cell dissociation reagent.

Supplier: STEMCELL Technologies

Immunomagnetic isolation of total lymphocytes directly from whole blood

Supplier: STEMCELL Technologies

Pre-aliquoted methylcellulose-based medium with recombinant cytokines for human cells. 24×3ml vials.

Supplier: STEMCELL Technologies

Mouse monoclonal antibody to human erythropoietin.

Supplier: STEMCELL Technologies

The EasySep™ Multistand allows the separation of up to four samples at one time.

Supplier: STEMCELL Technologies

Immunomagnetic positive selection of CD19+ cells (e.g. B cells) from mouse splenocytes or other tissues.

Supplier: STEMCELL Technologies

Differentiation kit for the generation of motor neurons from hPSCs.

Supplier: STEMCELL Technologies

Mouse monoclonal antibody against human, mouse, rat vimentin.

Supplier: STEMCELL Technologies

Rabbit polyclonal antibody against human, mouse, rat cytokeratin 20.

Supplier: STEMCELL Technologies

Serum-free neurophysiological basal medium for improved neuronal live imaging and function.

Supplier: STEMCELL Technologies

Immunomagnetic positive selection of any cells labeled with APC-conjugated antibodies.

Supplier: STEMCELL Technologies

Serum-free and animal component-free culture supplement for expansion of human B cells.

Supplier: STEMCELL Technologies

Measure and transfer liquids precisely and safely using Corning® Lambda™ Plus multi-channel pipettors.

Supplier: STEMCELL Technologies

Immunomagnetic depletion of human TCRa/b+ cells.

Supplier: STEMCELL Technologies

Fast and easy isolation of human extracellular vesicles using immunomagnetic positive selection.

Supplier: STEMCELL Technologies

Fast and easy isolation of human extracellular vesicles using immunomagnetic positive selection.

Supplier: STEMCELL Technologies

Immunomagnetic depletion of rat IgM+ cells.

Supplier: STEMCELL Technologies

Fibroblast growth factor 8A (FGF-8A) is a member of the fibroblast growth factor (FGF) family and is an isoform of FGF-8. FGF-8A binds the FGF receptor (FGFR) and activates Ras/MAPK signaling (Hulstrand and Houston). The FGF family possesses broad mitogenic and cell survival activities (Folkman and Klagsbrun; Kimelman and Kirschner) and is involved in a variety of biological processes, including cell proliferation, differentiation, survival, and apoptosis (Folkman and Klagsbrun; Klagsbrun; Rifkin and Moscatelli). FGF-8 RNA is spliced to produce 4 protein isoforms in humans: FGF-8A, FGF-8B, FGF-8E, and FGF-8F. The functional differences are not fully understood; however, studies in zebrafish and Xenopus show that FGF-8A is required for endoderm morphogenesis and neurogenesis (Choe and Crump; Hulstrand and Houston).

Supplier: STEMCELL Technologies

Activin A is a member of the transforming growth factor beta (TGF-β) family of proteins produced by many cell types throughout development (Gurdon et al.). It is a disulfide-linked homodimer (two beta-A chains) that binds to heteromeric complexes of a type I (Act RI-A and Act RI-B) and a type II (Act RII-A and Act RII-B) serine-threonine kinase receptor (Attisano et al.). Activins primarily signal through SMAD2/3 proteins to regulate a variety of functions, including cell proliferation, differentiation, wound healing, apoptosis, and metabolism (McDowell et al.). Activin A maintains the undifferentiated state of human embryonic stem cells (James et al.; Xiao et al.) and also facilitates differentiation of human embryonic stem cells into definitive endoderm (D’Amour et al.). This product is animal component-free.

Supplier: STEMCELL Technologies

Interleukin 2 (IL-2) is a monomeric cytokine that was originally identified as a T cell growth factor (Gaffen and Liu). It binds to heterotrimeric receptors consisting of CD25, CD122, and CD132. Upon binding, it activates JAK3-, STAT5-, and AKT-dependent signaling pathways, which results in cellular proliferation and survival (Ma et al.). The majority of IL-2 is secreted by activated CD4+ and CD8+ T cells, although B cells and dendritic cells were found to produce IL-2 in small amounts. IL-2 downregulates immune responses to prevent autoimmunity during thymic development, influences the development of CD4+CD25+ regulatory T cells, and affects development of follicular helper T cells. IL-2 also controls inflammation by inhibiting Th17 differentiation (Banchereau et al.). High IL-2 levels in serum are associated with progression of scleroderma, rheumatoid arthritis, and gastric and non-small cell lung cancer, though no known disease can be directly attributed to the lack or excess of IL-2 (Gaffen and Liu).