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mAbs scale-up: Success at every step.

Every step along the path to full-scale monoclonal antibody (mAb) production is critical and must be carefully chosen to avoid interruptions or delays. From the very beginning, we work with you to design an agile scale-up process using the right materials, systems and components for your specific mAb environment. We’ll help you plan early to plan for success.

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At Avantor®, we believe mAbs scale-up should be seamless, not siloed. You can rely on our technical expertise at every stage of development to customize a holistic manufacturing process for your unique mAb, using the right raw materials, tools and processes.

By adapting early to increasing volumes and more stringent regulatory requirements, we help you maintain consistent product quality and efficacy.

Our expert solutions for monoclonal antibody scale-up

Fluid Handling for Efficient mAbs Scale-Up

Two Masterflex peristaltic pumps with a human hand pointing at a touchscreen on one of the pumps for mAbs fluid transfer

From small scale to large, our technical experts and engineers help you reduce bottlenecks and product loss with closed system fluid transfer.

Smart equipment insights

Seamless mAbs Scale-Up from Research to GMP

Masked scientist wearing white coat and blue gloves writing notes on a glass board in a mAbs research lab

We ensure a smooth transition from Research Use Only (RUO) raw materials to GMP grade, avoiding delays that could put your market entry timeline at risk.

Get your GMP fact sheet

Customized mAbs Buffer Management

Several bottles of J.T.Baker Viral Inactivation Solution to demonstrate varying package size options for use in mAbs viral clearance

J.T. Baker® Viral Inactivation Solution

Improve viral inactivation efficiency and minimize introduction of impurities.

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Several bottles of PROchievA™ recombinant protein A to demonstrate varying package size options for use in mAbs chromatography

PROchievA™ recombinant protein A

Enhance your separation power and increase product purity.

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Learn More from Our Monoclonal Antibody Experts

  

Learn More from Our Monoclonal Antibody Experts