"Stemcell Technologies"

Supplier: Stemcell Technologies

Animal origin-free suspension culture medium for human ES and iPS cells.

Supplier: Stemcell Technologies

Maturation kit for generation of functional midbrain-type neurons from human ES and iPS cell-derived neuronal precursor cells.

Supplier: Stemcell Technologies

Mouse monoclonal IgG2a antibody against human CD51 (integrin αV), PE­conjugated.

Supplier: Stemcell Technologies

Vascular endothelial growth factor (VEGF-165) is a heparin-binding homodimeric glycoprotein involved in embryonic vasculogenesis and angiogenesis. VEGF binds to VEGFR-1 (R1) and VEGFR-2 (R2), and activates Raf/MEK/ERK and PI3K/AKT pathways (Ferrara et al.). It plays an important role in neurogenesis both in vitro and in vivo (Storkebaum et al.). It has neurotrophic effects on neurons of the central nervous system and promotes growth and survival of dopaminergic neurons and astrocytes. VEGF also promotes growth and survival of vascular endothelial cells, monocyte chemotaxis, and colony formation by granulocyte-macrophage progenitor cells (Ferrara et al.). VEGF-165 contains two polypeptide chains of 165 amino acids each. This product is animal component-free.

Supplier: Stemcell Technologies

Mouse monoclonal IgG1 antibody against human, chimpanzee, horse CD38, FITC-conjugated.

Supplier: Stemcell Technologies

Rat monoclonal IgG1 antibody against mouse CD25, unconjugated.

Supplier: Stemcell Technologies

Mouse monoclonal IgG1 antibody against human, rhesus, cynomolgus CD16, PE-conjugated.

Supplier: Stemcell Technologies

Media for maturation of human pluripotent stem cells derived blood vessels organoids.

Supplier: Stemcell Technologies

Neurotrophin-3 (NT-3) is a neurotrophic factor and a member of the nerve growth factor (NGF) family of proteins that includes neuron growth factor (NGF), brain-derived neurotrophic factor (BDNF), and neurotrophin-4/5. NT-3 signals a number of trophic effects through its transducing receptor tyrosine kinase TrkC. NT-3 is known to promote survival, development, and differentiation of neurons, and modulates transmitter release at several types of synapses in the peripheral and central nervous systems (Chalazonitis 1996). NT-3 has been shown to have an important role in the overall development of enteric neurons, which are crucial for gut peristalsis (Chalazonitis 2004). Studies in rats have shown the potential of NT-3 in dorsal column axonal regeneration (Bradbury et al.). NT-3 was shown to protect neurons against amyloid-β toxicity (Lesne et al.). NT-3 has applications in neuronal differentiation protocols to generate β-tubulin III+ peripheral neurons from neural crest stem cells (Menendez et al.) and oligodendrocyte precursor cells from human embryonic stem (ES) and induced pluripotent stem (iPS) cells (Douvaras et al.).

Supplier: Stemcell Technologies

Kit including BrainPhys™ neuronal medium, SM1 meuronal supplement and NeuroCult™ neuronal plating medium for culture of primary-derived neurons.

Supplier: Stemcell Technologies

Hamster (Armenian) monoclonal IgG2 antibody against mouse T cell receptor gamma/delta, PE-conjugated.

Supplier: Stemcell Technologies

Culture medium kit for extended maturation of human cerebral organoids.

Supplier: Stemcell Technologies

Activin A is a member of the transforming growth factor beta (TGF-β) family of proteins produced by many cell types throughout development (Gurdon et al.). It is a disulfide-linked homodimer (two beta-A chains) that binds to heteromeric complexes of a type I (Act RI-A and Act RI-B) and a type II (Act RII-A and Act RII-B) serine-threonine kinase receptor (Attisano et al.). Activins primarily signal through SMAD2/3 proteins to regulate a variety of functions, including cell proliferation, differentiation, wound healing, apoptosis, and metabolism (McDowell et al.). Activin A maintains the undifferentiated state of human embryonic stem cells (James et al.; Xiao et al.) and also facilitates differentiation of human embryonic stem cells into definitive endoderm (D’Amour et al.).

Supplier: Stemcell Technologies

For detection of active caspase-3 in mammalian cells undergoing apoptosis.

Supplier: Stemcell Technologies

cGMP, serum-free, and xeno-free medium for the expansion of human T cells.

Supplier: Stemcell Technologies

Supplement for hematopoietic differentiation optimised for lymphoid potential.