42864 Results for: "ProSci Inc."

Supplier: ProSci Inc.

Akirin2 peptide is used for blocking the activity of Akirin2 antibody.

Supplier: ProSci Inc.

Mouse beta -NGF is a neurotrophic factor structurally related to BDNF, NT-3 and NT-4. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. beta -NGF is a potent neurotrophic factor that signals through its receptor beta -NGFR, and plays a crucial role in the development and preservation of the sensory and sympathetic nervous systems. beta -NGF also acts as a growth and differentiation factor for B lymphocytes, and enhances B-cell survival.

Supplier: ProSci Inc.

MD-1 peptide is used for blocking the activity of MD-1 antibody.

Supplier: ProSci Inc.

ANGPT2 peptide is used for blocking the activity of ANGPT2 antibody.

Supplier: ProSci Inc.

Progranulin (PGRN) is a widely expressed pluripotent growth factor which plays a role in processes such as development, wound repair and inflammation by activating signalling cascades that control cell cycle progression and cell motility. Its function in the central nervous system is of interest, as mutations in the PGRN gene were found in cases of frontotemporal degeneration (FTLD). In addition, PGRN has also been linked to tumorigenesis. Progranulin is a biomarker for FTLD, other types of Alzheimer‘s Disease (AD) and potentially for MCI (Mild Cognitive Impairment). Additionally, PGRN is described as a new ligand of TNF receptors and a potential therapeutic against inflammatory disease like arthritis.

Supplier: ProSci Inc.

MADD peptide is used for blocking the activity of MADD antibody.

Supplier: ProSci Inc.

Recombinant Human Proprotein Convertase Subtilisin/Kexin Type 9/PCSK9 (D374Y) is a gain of function mutant of human PCSK9 protein. Human PCSK9 is a secretory subtilase belonging to the proteinase K subfamily. PCSK9 is synthesised as a soluble zymogen that undergoes autocatalytic intramolecular processing in the ER, the pro domain and mature chain are secreted together through noncovalent interactions. PCSK9 binds with low-density lipoprotein receptor (LDLR) and it plays a major regulatory role in cholesterol homeostasis. Inhibition of PCSK9 function by preventing PCSK9/LDLR interaction is currently being explored as a means of lowering cholesterol levels. PCSK9 also binds to apolipoprotein receptor 2 (ApoER2), and play a role in the neural development.

Supplier: ProSci Inc.

STEAP1 peptide is used for blocking the activity of STEAP2 antibody.

Supplier: ProSci Inc.

Glutaredoxin-1 (GRX1) is also known as Thioltransferase-1 (TTase-1), GLRX, GRX, GLRX1, which belongs to the glutaredoxin family. GRX1 / GLRX contains one glutaredoxin domain, which exists in either a reduced or an oxidized form. GRX1 / GLRX has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase and functions as electron carriers in the glutathione-dependent synthesis of deoxyribonucleotides by the enzymeribonucleotide reductase.

Supplier: ProSci Inc.

Annexin A10 (ANXA10) contains four Annexin repeats and is a member of the Annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. It is reported that ANXA10 may be a clinical relevant marker for predicting outcome in both early and advanced stages of bladder cancer.

Supplier: ProSci Inc.

RAIDD peptide is used for blocking the activity of RAIDD antibody.

Supplier: ProSci Inc.

Kit ligand (KITLG) is also known as stem cell factor (SCF), mast cell growth factor (MGF), steel factor (SF), which belongs to the SCF family, and is a widely expressed 28 - 40 kDa type I transmembrane glycoprotein. KITLG is the ligand for the receptor-type protein-tyrosine kinase KIT. SCF / MGF plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. KITLG / SCF binding can activate several signaling pathways. KITLG / SF Promotes phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, and subsequent activation of the kinase AKT1. KITLG / SCF and KIT also transmit signals via GRB2 and activation of RAS, RAF1 and the MAP kinases MAPK1/ERK2 and/or MAPK3/ERK1. KITLG / SCF and KIT promote activation of STAT family members STAT1, STAT3 and STAT5. KITLG / SCF and KIT promote activation of PLCG1, leading to the production of the cellular signaling molecules diacylglycerol and inositol 1, 4, 5 - trisphosphate. KITLG / SCF acts synergistically with other cytokines, probably interleukins.

Supplier: ProSci Inc.

TMEM18 peptide is used for blocking the activity of TMEM18 antibody.

Supplier: ProSci Inc.

GITR (Glucocorticoid-induced TNF receptor) is the receptor for TNFSF18. It is involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T cell receptor-mediated cell death. GITR serves as a negative regulator for NK cell activation. It mediates NF-kappaB activation via the TRAF2/NIK pathway.

Supplier: ProSci Inc.

Aldehyde dehydrogenase 1 family member A3 (ALDH1A3), also known as retinaldehyde dehydrogenase 3 (RALDH3), is a member of the aldehyde dehydrogenase family known to metabolise a wide variety of aldehydes.

Supplier: ProSci Inc.

CXCR4 peptide is used for blocking the activity of CXCR4 antibody.

Supplier: ProSci Inc.

SHANK3 peptide is used for blocking the activity of SHANK3 antibody.

Supplier: ProSci Inc.

For WB starting dilution is: 1:1000.

Supplier: ProSci Inc.

For WB starting dilution is: 1:1000.

Supplier: ProSci Inc.

For WB starting dilution is: 1:1000.

Supplier: ProSci Inc.

For WB starting dilution is: 1:1000.

Supplier: ProSci Inc.

For WB starting dilution is: 1:1000. For IHC-P starting dilution is: 1:10~50. For FACS starting dilution is: 1:10~50.

Supplier: ProSci Inc.

For WB starting dilution is: 1:1000.

Supplier: ProSci Inc.

For WB starting dilution is: 1:1000. For IHC-P starting dilution is: 1:50~100.

Supplier: ProSci Inc.

For WB starting dilution is: 1:1000. For IHC-P starting dilution is: 1:50~100.

Supplier: ProSci Inc.

Anti-Mouse Monoclonal Antibody [clone: [FluA-NP 4F1]] (HRP (Horseradish Peroxidase))

Supplier: ProSci Inc.

Zika membrane antibody can be stored at 4 to 730 °C for three months and –20 to +730 °C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Supplier: ProSci Inc.

Anti-ATL3 Rabbit Polyclonal Antibody

Supplier: ProSci Inc.

Anti-NET1 Rabbit Polyclonal Antibody

Supplier: ProSci Inc.

Anti-ABCD1 Rabbit Polyclonal Antibody