9315 Results for: "Fmoc-Lys(Z)-OH"

Supplier: ProSci Inc.

Lymphocyte Antigen 6H (LY6H) is a novel member of the LY6 family of glycosylphosphatidylinositol-anchored cell surface glycoproteins. LY6H contains one UPAR/Ly6 domain. Human LY6H is synthesized as a 140 amino acid precursor that contains a 25 amino acid signal sequence, 20 amino acid propeptide that is removed in the mature form, and a 90 amino acid mature chain. LY6H is highly expressed in the brain (cerebral cortex, amygdala, hippocampus and subthalamic nucleus) and in acute human leukemic cell line MOLT-3. It is also found in lower levels in testis, pancreas, small intestine and colon. It has been shown that LY6H may play a role in both the central nervous system and the immune system.

Supplier: MACHEREY-NAGEL

These ready-to-use Flash cartridges are designed for use in the Teledyne Isco® Companion® and other Teledyne Isco® CombiFlash® systems without additional connectors or capillaries or as stand-alone version for any pump/detector combinations.

Supplier: ProSci Inc.

CD84, also called SLAMF5, is a member of the CD2 subgroup of the immunoglobulin receptor superfamily. Members of this CD2 subgroup mediate signal transduction through the interaction of its immunoreceptor tyrosine-based switch motifs (ITSM) in the intracellular region and the SH2 domain of adaptor molecules SAP (SLAM-associated protein) and EAT-2 (EWS-activated transcript 2), and accordingly modulate both adaptive and innate immune responses. CD84 expression has been documented on several hematopoietic cell types, including monocytes, macrophages, dendritic cells, B lymphocytes, and platelets. Activation of cell surface CD84 initiates a signallling cascade involving its intra-cytoplasmic tyrosine residues that results in Bcl-2 upregulation, which in turn enhances cell survival. Either immunoneutralisation or blockade of CD84 with a CD84 extracellular domain protein fragment induces cell death in vitro and in vivo.

Supplier: TOSOH Bioscience

SkillPak 50 and 200 ml columns are designed for fast method development and scale-up and are pre-packed with TOYOPEARL® and TSKgel® process chromatography media. These columns offer superior separation of biomelocules, such as monoclonal antibodies, proteins and oligonucleotides. They are the best solution to scale up methods developed on SkillPak 1 and 5 ml pre-packed columns.

Supplier: TOSOH Bioscience

TSKgel® UP-SW Aggregate, the latest addition to the UP-SW series of silica-based size exclusion chromatography (SEC) columns, are specifically designed to facilitate the analysis of mAb aggregates, high molecular weight (MW) proteins and nulceic acids.

Supplier: TOSOH Bioscience

TSKgel® UP-SW2000 columns are designed for the analysis of small proteins, peptides and oligonucleotides. The columns are packed with 2 μm silica-based beads shielded with a hydrophilic diol-type bonded phase that prevents the silica surface from interacting with protein samples.

Supplier: Thermo Fisher Scientific

The proprietary hydrophilic bonded layer in these MAbPac SEC-1 Columns results in minimal non-desired interactions between the proteins and the stationary phase. The stationary phase is designed to handle different eluent conditions containing both high and low ionic strength mobile phases, as well as mass spectrometry friendly volatile eluents.

Supplier: Merck

Chromolith® DIOL columns are useful as an intermediate polarity media between C18 and silica. Diol functionalised media is less polar and can have different selectivity. Chromolith® DIOL can be used with a wide range of solvents in both normal and reverse phases. In normal phase mode, the diol phase provides an alternative selectivity compared to silica whilst additionally demonstrating longer retention times that help to obtain separation. In reverse phase mode, compounds such as water-soluble vitamins, sugars or amino acids are easily baseline separated using simple mobile phases. Chromolith® DIOL columns have long lifetimes within pH range of 2,5 to 7,5, high matrix tolerance and speed of analysis.

Supplier: ProSci Inc.

CD5 is a transmembrane glycoprotein of the conserved scavenger receptor cysteine-rich (SRCR) superfamily and expressed on thymocytes, peripheral T cells and a subset of B cells (B1-a). Moreover, CD5 also was found expressed in small lymphocytic lymphoma, hairy cell leukaemia and mantle cell lymphoma cells. The long cytoplasmic tail of CD5 has no intrinsic enzymatic activity, but contains four tyrosine phosphorylation sites, including an immunoreceptor tyrosine-based (ITAM)-like motif (pseudo-ITAM) and an immunoreceptor tyrosine-based inhibitory (ITIM)-like motif (pseudo-ITIM), as well as multiple potential serine and threonine phosphorylation sites. It physically associates with the T cell antigen receptor (TCR) and B cell antigen receptor (BCR), where it negatively modulates the activation and differentiation signals transduced by these receptors. CD5 also plays an important role in protection from activation-induced cell death and in the recognition of pathogen associated molecular patterns (PAMPS) present on fungal surfaces.

Supplier: Thermo Fisher Scientific

A short alkyl chains with polar functional groups are ideal for the isolation of polar compounds.

Supplier: Resonac

PROTEIN KW-800 and KW400 series HPLC columns are specifically designed for protein analysis by aqueous size exclusion chromatography (GFC). PROTEIN LW-803 and LW-403 4D are designed for antibody analysis. They are packed with porous silica particles coated with a hydrophilic copolymer. They fulfill USP L20, L33, and L59 requirements.

Supplier: TOSOH Bioscience

SkillPak 1 and 5 ml columns are designed for fast method development, resin screening or sample concentration. Pre-packed with TOYOPEARL®, TSKgel® or Ca++Pure-HA™ process chromatography media, these columns offer superior separation of biomelocules, such as monoclonal antibodies, proteins and oligonucleotides. SkillPak 50 and 200 ml pre-packed columns are the best solution for seamless scale up of methods developed on SkillPak 1 and 5.

Supplier: PerkinElmer

Standard rectangular macro cuvettes frequently used in spectroscopy for routine liquids analysis. They have cell windows that are fused to the bodies by a special process which avoids deformation of the windows. This assures that the full width of the cell is usable and the finished cell dimensions are maintained.

Supplier: Abcam

A rapid sandwich ELISA kit for quantify 8-OHdG in rat serum, plasma, urine and other biological fluid.

Supplier: Merck

LiChrospher® is Merck's reliable and versatile, traditionally-produced, spherical silica. LiChrospher® is available with different modifications.