12561 Results for: "Enzo Life Sciences"
Anti-SIRT5 Rabbit Polyclonal Antibody
Supplier: Enzo Life Sciences
SIRT5 is the only human class III sirtuin and as such is the closest homolog to bacterial (e.g. E. coli CobB) and archaeal sirtuins. SIRT5 is an imported mitochondrial protein with a calculated precursor molecular weight of 34kDa. In various human, rat, mouse and bovine cells and tissues, the major reactive band migrates with an apparent molecular weight of ~29kDa. This presumably reflects removal of an N-terminal transit sequence due to mitochondrial import and processing. No cross-reactivity observed with recombinant human sirtuins SIRT1, SIRT2 or SIRT3.
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4,5,6,7-Tetrachloro-1H-indene-1,3(2H)-dione ≥95% (by TLC)
Supplier: Enzo Life Sciences
Novel inhibitor of ubiquitin C-terminal hydrolase L3 (IC50 = 0.6µM). Displays 125-fold greater selectivity over UCH-L1 (IC50 = 75µM).
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cis-5,8,11-Eicosatrienoic acid ≥97% (by HPLC), colourless oil
Supplier: Enzo Life Sciences
Immunomodulatory and anti-inflammatory effects.
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5,8,11,14-Eicosatetraynoic acid ≥98%
Supplier: Enzo Life Sciences
Arachidonic acid uptake inhibitor
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N-Arachidonylglycine ≥98% (by TLC)
Supplier: Enzo Life Sciences
FAAH inhibitor
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SB216763 ≥98% (by TLC)
Supplier: Enzo Life Sciences
Potent and selective inhibitor of GSK-3β (IC50=34nM). Stimulates glycogen synthesis in human liver cells and mimics other actions of insulin. Protects primary neurons from death induced by PI-3 kinase pathway inhibition suggesting therapeutic potential in neurodegenerative diseases and stroke. Reduces pulmonary inflammation and fibrosis in a mouse model.
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HC-030031 ≥98% (by HPLC)
Supplier: Enzo Life Sciences
A potent and selective TRPA1 inhibitor.
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L-cis-Diltiazem HCl ≥98%
Supplier: Enzo Life Sciences
Ca²⁺ channel blocker.
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Fluphenazine-N-2-chloroethane 2HCl ≥98%
Supplier: Enzo Life Sciences
A potent irreversible inactivator of calmodulin. Possesses potent antiproliferative and cytotoxic activity. It is also an irreversible D2 dopamine receptor antagonist.
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Nourseothricin sulphate (from Streptomyces noursei) ≥85%
Supplier: Enzo Life Sciences
Antibiotic
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5Z-7-Oxozeaenol (from Deuteromycetes sp.) ≥95% (by HPLC)
Supplier: Enzo Life Sciences
Inhibitor of the JNK/p38 pathways. Inhibits anisomycin-induced but not TNF-induced JNK/p38 activation. Potent protein kinase inhibitor
>A naturally isolated cell-permeable fungal resorcylic lactone that acts as a selective and highly potent inhibitor against the MAPKKK TAK1 activity (IC50 = 8nM) in an ATP-competitive and irreversible manner; also inhibits MEK1 (IC50 = 411nM) and three other MAPKKKs (IC50 ≥268 nM against MEKK1, ASK1, and MEKK4) but at much higher concentrations. Shown to inhibit IL-1-induced/TAK1-mediated, but not H2O2-induced/TAK1-independent, JNK and p38 phosphorylation in 293 cells.
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Daunorubicin hydrochloride (from Streptomyces species)
Supplier: Enzo Life Sciences
Antitumor antibiotic.
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Nadifloxacin ≥98%
Supplier: Enzo Life Sciences
Fluoroquinolone with broad spectrum activity against Gram-negative and Gram-positive bacteria. Inhibits the generation of O2- and OH radicals by neutrophils. Inhibits the production of inflammatory cytokines.
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Enniatin A (from Fusarium sp.) ≥97% (by HPLC)
Supplier: Enzo Life Sciences
White to off-white crystalline solid
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Streptomycin sulphate (from Streptomyces species)
Supplier: Enzo Life Sciences
Antibiotic. Inhibits prokaryote protein synthesis. Binds to the S12 protein of the 30S ribosomal subunit. Effective against Gram-negative and Gram-positive bacteria. Mutation in rpsL (the gene for S12 ribosomal protein) prevents binding of streptomycin to ribosome. Inactivated by aminoglycoside phosphotransferase.
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Sparfloxacin ≥98%
Supplier: Enzo Life Sciences
Fluoroquinolone with broad spectrum antibacterial activity against Gram-positive and Gram-negative bacteria. Inhibits bacterial DNA gyrase (topoisomerase). Effective against Mycobacterium tuberculosis. Shows photosensitizing effects.
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Hygromycin B solution in PBS, sterile filtered
Supplier: Enzo Life Sciences
Hygromycin B solution in PBS, sterile filtered
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Quercetin dihydrate ≥95% (by HPLC)
Supplier: Enzo Life Sciences
Antioxidant flavonoid
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3,4',5,7-Tetrahydroxy-3'-methoxy flavylium chloride ≥97% (by HPLC)
Supplier: Enzo Life Sciences
Anti-inflammatory and chemopreventive. Antioxidant flavonoid.
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Microcystis aeruginosa Microcystin HTYR
Supplier: Enzo Life Sciences
Microcystins are a group of cyclic heptapeptide hepatotoxins produced by a number of cyanobacterial genera. The most notable of which, and namesake, is the widespread genus Microcystis. Structurally, all microcystins consist of the generalized structure cyclo(-D-Ala1-X2-D-MeAsp3-Y4-Adda5-D-Glu6-Mdha7-). X and Y are variable L-amino acids, D-MeAsp is D-erythro-β-methylaspartic acid and Mdha is N-methyldehydroalanine. Adda is the cyanobacteria unique C20 β-amino acid 3-amino-9-methoxy-2,6,8-trimethyl-10-phenyl-deca-4,6-dienoic acid. Substitutions of the variable L-amino acids at positions 2 and 4 give rise to at least 21 known primary microcystin analogs and alterations in the other constituent amino acids result in more than 90 reported mycrocystins to date.
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Cylindrospermopsin ≥95% (by HPLC)
Supplier: Enzo Life Sciences
Protein synthesis inhibitor
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Nomilin ≥98% (by HPLC)
Supplier: Enzo Life Sciences
Carciogenesis inhibitor
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Supplier: GRANT INSTRUMENTS
Supplier: BOCHEM
Supplier: VWR Collection
Supplier: OMEGA BIO-TEK
Supplier: DWK Life Sciences
Supplier: Thermo Fisher Scientific
Supplier: VWR Collection
Supplier: Oxford Nanopore Technologies
Supplier: Industrial Physics
Supplier: AAT Bioquest
Supplier: Integra
Supplier: Palbam
Supplier: VWR Collection
Supplier: Integra
Supplier: VWR Collection
Supplier: FACELLITATE
Supplier: NANOENTEK
Supplier: Greiner Bio-One