Amine-reactive quencher dye has a broad visible absorption but no detectable fluorescence emission in fluorescence resonance energy transfer (FRET) applications.

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The kit offers a set of six different MAbs specific for serine phosphorylation sites. Phosphorylation patterns in a given cell extract may differ when probed with different antibodies due to sequence specificity. Recognition therefore depends on two criteria: phosphorylation and surrounding aa motif. If one of the two criteria is not fulfilled, the antibody will not detect the phosphorylation site. Specificity has been determined by epitope mapping using degenerated phosphopeptide libraries. Clone 16B4 strongly interacts with pSK and pSP motifs, thus specifically recognizes substrates of MAP/SAP Kinases and CDC kinases.Clones 1C8, 4A3, 4A9, 4H4 and 7F12 interact with epitopes containing phosphoserine in the context of positive or neutral aa (e.g. substrates of PKA, PKB, PKC, PKG etc.) Though revealing a similar pattern in epitope mapping using phosphopeptide libraries, these antibodies interact with different sets of phosphoproteins in whole cell lysates.

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Anti-MT Rabbit Polyclonal Antibody

Supplier: Enzo Life Sciences

Host: Rabbit, Isotype: IgG

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Caspase inhibitor set

Supplier: Enzo Life Sciences

Synthetic peptides that irreversibly inhibit the activity of each of the caspase-family proteases. YVAD is the recognition sequence for caspase-1/ICE, DEVD is the recognition sequence for caspase-3/CPP32, VEID is the recognition sequence for caspase-6/Mch2, IETD is the recognition sequence for caspase-8/ FLICE, and VAD is the recognition sequence for a caspase(s) that functions upstream of most other caspases.

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Anti-Nephrin Rabbit Polyclonal Antibody

Supplier: Enzo Life Sciences

Host: Rabbit, Isotype: IgG

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IgM (mouse), ELISA kit

Supplier: Enzo Life Sciences

For the quantitative determination of IgM in ascites fluid, culture supernatants, and serum of mouse origin.

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Myeloperoxidase (human), ELISA kit

Supplier: Enzo Life Sciences

For the quantitative determination of human Myeloperoxidase of culture supernatants, nasal lavage, Lithium-heparin plasma, sputum supernatant, and urine.

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GRO/CINC-1 (Rat), ELISA kit

Supplier: Enzo Life Sciences

The GRO/CINC-1 (Rat), EIA kit is a colorimetric immunometric enzyme immunoassay kit with results in 2 hours. Absorbance is read at 450 nm. Assay up to 39 samples in duplicate per kit.

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IL-2 (human), ELISA kit

Supplier: Enzo Life Sciences

The IL-2 (human), EIA kit is a colorimetric immunometric enzyme immunoassay kit with results in 3 hours.

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IFN-gamma (human), ELISA kit

Supplier: Enzo Life Sciences

The IFN-gamma (Human), EIA kit is a colorimetric immunometric enzyme immunoassay kit with results in 3 hours. Absorbance is read at 450 nm.

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Comet SCGE assay kit

Supplier: Enzo Life Sciences

COMET SCGE Assay measures DNA damage by fluorescently detecting the integrity of DNA liberated from cells embedded in low melting point agarose. Upon electrophoresis, fragmented DNA produces a characteristic "comet" shaped tail as small DNA fragments migrate in the gel more rapidly than in-tact genomic DNA.

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Mouse recombinant IL-3

Supplier: Enzo Life Sciences

Produced in E. coli. Non-glycosylated protein, containing 135 amino acids.

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Lucigenin ≥98% (by HPLC), Ultrapure

Supplier: Enzo Life Sciences

Chloride dye

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FluoForte™ Reagent

Supplier: Enzo Life Sciences

Calcium dye

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U-75302 ≥98% (by TLC)

Supplier: Enzo Life Sciences

Prostanoid receptor ligand.

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SC-51322 ≥98%

Supplier: Enzo Life Sciences

Prostanoid receptor inhibitor

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Seratrodast ≥98%

Supplier: Enzo Life Sciences

Thromboxane receptor ligand.

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BML-111 ≥99%

Supplier: Enzo Life Sciences

Potent lipoxin A₄ agonist, equiactive as LXA₄ in inhibition of LTB₄ induced PMNL chemotaxis (IC₅₀ = 5 nM).

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Anti-Proteasome 19S Rpn10/S5A Subunit Mouse Monoclonal Antibody

Supplier: Enzo Life Sciences

Host: Mouse, Isotype: IgG1

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Tyrphostin A25 ≥99%

Supplier: Enzo Life Sciences

A potent inhibitor of EGF receptor kinase activity (IC50=3 µM).

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D-erythro-Sphingosine ≥98% (by TLC)

Supplier: Enzo Life Sciences

Common component of cell membranes, often as phosphatidyl conjugates. Is a potent (IC50=1-3 µM) and selective inhibitor of protein kinase C. Inhibition is competitive with diacylglycerol, phorbol dibutyrate and Ca2+ and it also inhibits PKC activation by other lipids. It acts on an equimolar basis with 1,2-dioleoylglycerol and does not affect other kinases such as MLCK and PKA. It is active in intact cells and has been identified as an endogenous constituent in HL-60 cells, neutrophils, rat liver, and brain and mouse tissues. Other activities include inhibition of phosphatidate phosphohydrolase, Na+,K+-ATPase, CTP:phosphocholine cytidylyltransferase, calmodulin-dependent enzymes, binding of factor VII to tissue factor, binding of thyrotropin releasing hormone to its receptor and activation of EGF receptor kinase, phospholipase D and casein kinase II.

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21-[4-(2,6-Di-1-pyrrolidinyl-4-pyrimidinyl)-1-piperazinyl]pregna-1,4,9[11]triene-3,20-dione maleate salt ≥98% (by TLC)

Supplier: Enzo Life Sciences

Blocks lipid peroxidation

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Chaetomellic acid A ≥98% (by TLC)

Supplier: Enzo Life Sciences

Potent inhibitor of farnesyltransferase in isolated enzyme assays (IC50=55nM) but is inactive in whole cells. Inhibition of farnesyltransferase is selective over geranylgeranyltransferase I and II (IC50=92µM and 34µM respectively).