12561 Results for: "Enzo Life Sciences"

Supplier: Enzo Life Sciences

Anti-TAPBP Rabbit Polyclonal Antibody

Supplier: Enzo Life Sciences

Produced in E.coli.

Supplier: Enzo Life Sciences

Produced in E. coli. Human ARH1 is fused at the C-terminus to a His-tag.

Supplier: Enzo Life Sciences

Inhibitor of PP1 and PP2A

Supplier: Enzo Life Sciences

Host: Mouse, Isotype: IgG1

Supplier: Enzo Life Sciences

PKG inhibitor

Supplier: Enzo Life Sciences

TPA/PMA inhibitor

Supplier: Enzo Life Sciences

TPA/PMA inhibitor

Supplier: Enzo Life Sciences

The Screen-Well® histaminergic and melatonin ligands plate contains 41 ligands including endogenous neurotransmitters, agonists, antagonists, and marketed drugs. The library is ideal for screening or identifying recombinant orphan G protein coupled receptors, target validation, secondary screening, assay development, and other pharmacological applications. The Histaminergic and Melatonin Ligands plate is 1 plate of the larger neurotransmitter library which contains over 680 ligands.

Supplier: Enzo Life Sciences

Screen-Well™ REDOX library contains 84 compounds with defined prooxidant or antioxidant activity.

Supplier: Enzo Life Sciences

Ionophore antibiotic. Induces apoptotic cell death in H4IIE hepatoma cells accompanied by inhibition of ERK phosphorylation.

Supplier: Enzo Life Sciences

Produced in E. coli. E. coli DnaJ is fused at the N-terminus to a His-tag.

Supplier: Enzo Life Sciences

Antibody sample pack includes a set of related GPCR polyclonal antibodies for pain research.

Supplier: Enzo Life Sciences

The caspases are a family of cysteine proteases that cleave after certain aspartate residues, and are primarily recognized as mediators of apoptosis. caspases are synthesized as inactive zymogens that can be cleaved to form active enzymes following the induction of apoptosis by stress or death receptors. Initiator caspases (e.g. caspase-8 and -10) are activated by dimerization of the zymogen on a dedicated adaptor protein. These activated initiator caspases in-turn cleave downstream effector or executioner caspases (e.g. caspase-3, -6, and -7) in a cascade-like manner, which cleave key cellular proteins that lead to the morphological changes associated with apoptotic cell death.

Supplier: Enzo Life Sciences

Hsp60 is a member of the chaperonin family of heat shock proteins, with homologs functioning in the cytosol and mitochondria to fold nascent and aggregated proteins. Hsp60 is the eukaryotic homolog of the E. coli GroEL protein, and forms a multimeric complex in the mitochondria with Hsp10 (Cpn10) to form a large central cavity in which ATP-dependent protein folding takes place. TRiC/CCT, a eukaryotic relative of Hsp60, is expressed in the cytosol and participates in the folding of actin and tubulin substrates, but lacks any association with an Hsp10-like co-factor.

Supplier: Enzo Life Sciences

The Hsp90 family of heat shock proteins represents one of the most abundantly expressed and highly conserved families of cellular chaperones whose expression can be upregulated under conditions of cellular stress, and includes cytoplasmic (Hsp90-alpha/beta), ER (grp94), and mitochondrial (TRAP1) localized members. Structurally, Hsp90 is characterized by an N-terminal ATP-binding domain, a medial substrate-binding domain, and a C-terminal dimerization motif. Hsp90 dimers function in cooperation with cochaperones (e.g. Hsp40, Hsp70, Hop, p23) to stabilize a multitude of client protein substrates, including steroid hormone receptors, protein kinases, and transcription factors. The essential binding and hydrolysis of ATP by Hsp90 is inhibited by ansamycin drugs (e.g. geldanamycin, 17-AAG) which occupy the N-terminal Hsp90 nucleotide-binding pocket. Many Hsp90 client proteins such as erbB2/Her-2, c-raf, bcr-abl, p53, and hTERT, are members of well characterized oncogenic pathways, making Hsp90 inhibitors useful anticancer agents.

Supplier: Enzo Life Sciences

Beneficial effect in cardiovascular diseases and inflammation. Inhibits PGE2 formation from arachidonic acid in 3T3 fibroblats.

Supplier: Enzo Life Sciences

TLR9 ligand.

Supplier: Enzo Life Sciences

Inhibits platelet aggregation. Inhibitor of Epstein-Barr virus early antigen (EBV-EA) induction. Exhibits potent inhibitory effect on skin tumor promotion. Potent inhibitor of MMP-2. Displays DNA strand-scission (cleaving) activity. Shows antifungal activity.

Supplier: Enzo Life Sciences

From herpes simplex virus type 1. Inactivated by 0.1% Triton X-100.

Supplier: Enzo Life Sciences

TLR9 ligand.

Supplier: Enzo Life Sciences

Inhibitor of PP2A and calcineurin

Supplier: Enzo Life Sciences

TLR9 ligand.

Supplier: Enzo Life Sciences

TLR9 ligand.

Supplier: Enzo Life Sciences

Antifungal agent

Supplier: Enzo Life Sciences

DcR1 is a 65kDa GPI-anchored member of the TNFR superfamily (TNFRSF10C) also known as TRAIL-R3, TRID, CD263, and LIT. Although not expressed by most tumors, DcR1 is expressed at low levels on normal tissues, acting as a TRAIL decoy receptor, thus inhibiting apoptosis. DcR1 is termed a decoy receptor, as it does not have a functional death domain to induce apoptosis following TRAIL ligation.

Supplier: Enzo Life Sciences

Antibiotic. Potent inhibitor of protein kinase C (PKC). Inhibits the cell cycle at the G2 stage.

Supplier: Enzo Life Sciences

Inhibitor of testosterone 5-reductase and P-ATPase

Supplier: Enzo Life Sciences

Inhibits PKA (Ki=3.0μM), PKG (Ki=5.8μM), MLCK (Ki=97μM) and PKC (Ki=6μM). Also inhibits myosin light chain kinase. Induces apoptotic DNA fragmentation and cell death. Inhibits telomerase activity in treated NPC-076 cells. Cell permeable.

Supplier: Enzo Life Sciences

Host: Rabbit