12561 Results for: "ENZO LIFE SCIENCES"
Anti-PTGDS Rabbit Polyclonal Antibody
Supplier: Enzo Life Sciences
PGD2 is a principal metabolite of arachidonic acid, catalyzed by PGD synthases primarily in hematopoietic and neural cells. Although PGD2 is traditionally considered a pro-inflammatory mediator, the actions of PGD2 and its metabolites have been shown to exert concentration-dependent pro- and anti-inflammatory effects on leukocyte development, function, and apoptosis.
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Anti-IL8 Mouse Monoclonal Antibody [clone: NYR-HIL8]
Supplier: Enzo Life Sciences
Interleukin-8 (IL-8) is a cytokine produced by monocytes, macrophages, neutrophils, lymphocytes, dermal fibroblasts, keratinocytes, vascular endothelial cells, melanocytes, hepatocytes and various tumor cell lines. It is also a member of the CXC family of chemokines, displaying chemotactic activity for neutrophils and T cells.
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Anti-8-ISO-PGF2 alpha Rabbit Polyclonal Antibody
Supplier: Enzo Life Sciences
Prostaglandin F2alpha (PGF2alpha) is formed in a variety of cells from PGH2, which itself is synthesized from arachidonic acid by the enzyme prostaglandin synthetase. PGF2alpha is often viewed as an antagonist to PGE2 due to their opposing effects on various tissues. PGF2alpha is a potent bronchoconstrictor and has been implicated in asthma attacks. PGF2alpha is also involved in reproductive functions including corpus luteum regulation, uterine contractions, and sperm motility. This has led to its use in terminating pregnancies and inducing labor at term. High levels of PGF2alpha have also been associated with preeclampsia.
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Why Choose Corning Fetal Bovine Serum?
Our vertically integrated FBS serum supply chain, from collection to scientist, allows us to provide a consistent supply of FBS.
SMER28 (synthetic) ≥98% (by TLC)
Supplier: Enzo Life Sciences
Small molecule inducer of autophagy important for neurodegenerative disease research.
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VAS-2870 ≥98% (by HPLC)
Supplier: Enzo Life Sciences
Novel inhibitor of NAD(P)H oxidase (Nox). In vascular smooth muscle cells VAS-2870 completely abolished PDGF-mediated NAD(P)H oxidase activation and ROS production (100% at 10µM). It inhibits PDGF-induced chemotaxis but not proliferation of VSMC. In mouse embryonic stem cells VAS-2870 blocked PDGF-BB-induced vasculogenesis. OxLDL-induced ROS formation in human endothelial cells was completely inhibited by VAS-2870 (100% at 5µM). VAS-2870 inhibits PMS-induced oxidative burst in HL-60 cells (IC50=2µM).
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Src inhibitor-1 ≥98% (by HPLC)
Supplier: Enzo Life Sciences
Potent, dual site (ATP domain and substrate-binding domain) Src and Lck kinase inhibitor (IC50=44 and 88nM respectively). VEGFR2 IC50=0.32μM; c-fms IC50=30μM.
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Anti-PARP3 Rabbit Polyclonal Antibody
Supplier: Enzo Life Sciences
PARP-3 is part of the PARP family of enzymes that modify nuclear proteins by poly-ADP-ribosylation, which is required for DNA repair, regulation of apoptosis, and maintenance of genomic stability. This gene encodes the poly(ADP-ribosyl)transferase 3, which is preferentially localized to the daughter centriole throughout the cell cycle. Alternatively spliced transcript variants encoding different isoforms have been identified.
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Human recombinant SGK-1 (truncated NT 60 aa) (from insect cells (Sf9)), GST Tag
Supplier: Enzo Life Sciences
Active recombinant human SGK-1 (truncated NT 60 aa) produced in Sf9 cells using an N-terminal GST-tag.
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Anti-ESR Rabbit Polyclonal Antibody
Supplier: Enzo Life Sciences
Cysteine string protein (CSP) is a 34 kDa rat brain protein localized to the cytoplasmic surface of the synaptic vesicle. CSP is believed to perform similar functions in the assembly of synaptic vesicle proteins which are essential to membrane trafficking.
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Anti-SHPS-1/SIRP-1 alpha Rabbit Polyclonal Antibody
Supplier: Enzo Life Sciences
SHPS-1 is a member of the gene family called the signal regulatory proteins of which there are at least fifteen members. SHPS-1 is a substrate of many activated tyrosine kinases such as Insulin receptor and EGFR, amongst others. SHPS-1 has regulatory effects on cellular responses induced by serum, growth factors, insulin, oncogenes, growth hormones and cell adhesion and plays a general role in different physiological and pathological processes.
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Anti-Y Rabbit Polyclonal Antibody
Supplier: Enzo Life Sciences
Protein phosphorylation is a complex biochemical process that is regulated by protein kinases that catalyze the transfer of the gamma-P of ATP to a recipient protein that acts as a substrate. This post-translational modification is primarily directed onto serine, threonine, and tyrosine amino acid residues within a protein. Changes in the phosphorylation status of phosphoproteins can alter their biological function, and aberrations in signal transduction cascades have been linked to a number of diseases, including cancer, diabetes, heart disease, inflammation and neurological disorders.
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Rat recombinant USP2 (catalytic domain) (from E. coli)
Supplier: Enzo Life Sciences
Produced in E. coli. Untagged USP2 catalytic domain.
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Anti-RAB4 Rabbit Polyclonal Antibody
Supplier: Enzo Life Sciences
The Rab family of GTP-binding proteins are members of the Ras superfamily of small G proteins, and participate in multiple steps of the membrane trafficking. Rab3A participates in the fusion of synaptic vesicles during neurotransmitter release, a process regulated by GDP/GDP exchange cofactors such as GAP, GDI, GRF, and rabphilin. Rab4 regulates recycling of proteins from the early endosome to the surface of many cell types, regulating glucose transporter and transferrin receptor cell surface localization. Rab5 regulates the fusion of plasma membrane-derived clathrin-coated vesicles with early endosomes and homotypic fusion among early endosomes.
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Anti-UGGT Rabbit Polyclonal Antibody
Supplier: Enzo Life Sciences
UDP-glucose:glycoprotein glucosyltransferase (UGGT) is a 170 kDa lumenal endoplasmic reticulum (ER) resident protein that catalyzes monoglucosylation of high mannose oligosaccharides. UGGT catalyzes the transfer of glucose from UDP-glucose to Man7-9GlcNAc2-moiety of unfolded glycoproteins in a Ca2+ dependent reaction. UGGT binds unfolded glycoprotein via an N-acetylglucosamine unit on the oligosaccharide, and hydrophobic amino acids that are exposed in the denatured conformation.
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Recombinant Coronavirus (CoV-NP-NL63) Antigen (from E. coli)
Supplier: Enzo Life Sciences
Produced in E. coli. Recombinant protein (130 aa).
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Human Recombinant PDGF-BB (from E. coli)
Supplier: Enzo Life Sciences
Produced in E. coli. Contains 110/220 amino acids.
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Human Recombinant PDGF-AB (from E. coli)
Supplier: Enzo Life Sciences
Produced in E. coli. Contains 126, 110/236 amino acids.
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Zika Virus -NS1 (Uganda Strain) (from HEK293 cells)
Supplier: Enzo Life Sciences
Recombinant Zika Virus (Uganda strain) NS1 protein, incorporating a C-terminal 6x His tag produced in mammalian HEK293 cells.
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Anti-CDH5 Mouse Monoclonal Antibody
Supplier: Enzo Life Sciences
Host: Mouse, Isotype: IgG2a
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Anti-CYP2C8 Sheep Polyclonal Antibody
Supplier: Enzo Life Sciences
Mephytoin 4-hydroxylase family of CYPs. Metabolizes anti-depressants. Cytochrome P-450 2C19 (CYP2C19) is a sex-dependent steroid hydroxylase.
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Anti-GOLGB1 Rabbit Polyclonal Antibody
Supplier: Enzo Life Sciences
Recommended Applications: IF, WB
Species reactivity: Human, Rodent, Monkey
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Anti-HOXB1 Rabbit Polyclonal Antibody
Supplier: Enzo Life Sciences
Recommended Applications: IHC, WB
Species reactivity: Mouse, Primate
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Anti-CYP2B6 Rabbit Polyclonal Antibody
Supplier: Enzo Life Sciences
Recommended Applications: IF, IHC (PS), WB
Species reactivity: Human
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Anti-IgG Goat Polyclonal Antibody (HRP (Horseradish Peroxidase))
Supplier: Enzo Life Sciences
Immunoglobulin G (IgG) is an immunoglobulin monomer consisting of two (gamma) heavy chains and two light chains. Each IgG molecule contains two antigen binding domains and a single effector (Fc) domain. Assay Designs offers isotyping kits and antibodies in a variety of formats for the detection of human, mouse, rabbit, rat, sheep, and goat IgG.
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Anti-CYP1A2 Rabbit Polyclonal Antibody
Supplier: Enzo Life Sciences
Members of the cytochrome P-450 1A (CYP1A) sub-family are induced by a range of polycyclic aromatic compounds such as benzpyrene, 3-methylcholanthrene (Prod. No. BML-GR239), and pro-carcinogenic heterocyclic aromatic amines. Cigarette smoking has been reported to induce CYP1A2 in human liver, and appears to be a major catalyst in the hepatic activation of PhIP, (2-amino-1-methyl-6-phenylimidazo[4,5,b]-pyridine). The mono-oxygenase inhibitor inhibitor enoxacin induces CYP1A2 in rat liver, whereas a related compound ciprofloxacin does not.
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Anti-CD40 Mouse Monoclonal Antibody (Alexa Fluor® 647) [clone: mAb 89]
Supplier: Enzo Life Sciences
Recommended Applications: Flow Cytometry, IF
Species reactivity: Human
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Anti-KRT19 Mouse Monoclonal Antibody [clone: RCK 108]
Supplier: Enzo Life Sciences
Recommended Applications: ICC, IHC, WB
Species reactivity: Human
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Anti-LCN2 Mouse Monoclonal Antibody
Supplier: Enzo Life Sciences
Rat lipocalin-2 is also called rat NGAL, as it is the ortholog of human neutrophil gelatinase-associated lipocalin (NGAL). Rat NGAL is a 25-kDa alpha 2-microglobulin-related protein or neu-related lipocalin. It is expressed by neutrophils and various epithelial cells, including cells of the renal proximal tubules. It is involved in physiological processes such as the binding of siderophore iron and tissue growth and regeneration. It is upregulated in a variety of pathological situations including infection, inflammation, ischemia-reperfusion and in certain adenocarcinomas.
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Anti-GHRL Mouse Monoclonal Antibody [clone: 45]
Supplier: Enzo Life Sciences
Anti-GHRL Mouse Monoclonal Antibody [clone: 45]
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12(S)-HETE ELISA kit
Supplier: Enzo Life Sciences
Sensitive ELISA kit enabling detection of 12(S)-HETE in culture supernatants and plasma from any species.