12561 Results for: "ENZO LIFE SCIENCES"
NUCLEAR-ID® ≥95% (by HPLC), CELLESTIAL® blue DNA stain
Supplier: ENZO LIFE SCIENCES
Cell permeable DNA stain that can be used for a wide range of applications
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Anti-ITGB1 Mouse Monoclonal Antibody
Supplier: ENZO LIFE SCIENCES
Host: Mouse, Isotype: IgG1
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Anti-BCMA Rat Monoclonal Antibody (FITC) [clone: Vicky-1]
Supplier: ENZO LIFE SCIENCES
Recommended Applications: Flow Cytometry
Species reactivity: Human
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Why Choose Corning Fetal Bovine Serum?
Our vertically integrated FBS serum supply chain, from collection to scientist, allows us to provide a consistent supply of FBS.
Native Hsv-1 antigen
Supplier: ENZO LIFE SCIENCES
From herpes simplex virus type 1. Inactivated by 0.1% Triton X-100.
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Di-Ubiquitin (linear) (from E. coli)
Supplier: ENZO LIFE SCIENCES
Linear polyubiquitin chains are useful tools for investigating, amongst other things, the specificity and reactivity of deubiquitinylating enzymes (DUBs) and the recognition and interaction of linear polyubiquitin modified proteins with ubiquitin binding domain (UBDs) containing proteins.
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Sphingomyelin ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Purified from bovine brain. Contains primarily stearic and nervoic acids. Precursor to ceramide second messengers via the action of sphingomyelinase.
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Anti-OPN Mouse Monoclonal Antibody [clone: 53]
Supplier: ENZO LIFE SCIENCES
Osteopontin (OPN) is an acidic extracellular matrix cell adhesion protein that is relatively abundant not only in bone matrix, plasma, urine, and milk, but is also found in malignant and atherogenic tissues. Phosphorylation, glycosylation and calcium modifications allow intact and fragmented Osteopontin to direct a variety of diverse responses including tissue remodeling, inflammation and cell survival. Plasma Osteopontin has been shown to provide prognostic information in breast, prostate, colon, and lung cancers as well as metastatic carcinomas. The notable presence of Osteopontin in a variety of tumors is strongly correlated to pathological stage, suggesting its critical role in tumor invasiveness, progression and metastasis. In addition, Osteopontin inhibits inducible nitric oxide synthase activity, thereby protecting tumor cells from NO-mediated macrophage cytotoxic attack. Osteopontin is found in atherosclerotic plaques and may drive a number of diabetic vascular pathologies.
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Anti-UNC5B Mouse Monoclonal Antibody
Supplier: ENZO LIFE SCIENCES
Host: Mouse, Isotype: IgG2b
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Anti-BCL2L2 Rat Monoclonal Antibody
Supplier: ENZO LIFE SCIENCES
Host: Rat, Isotype: IgG2a
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Matrix Metalloproteinase-1 (MMP-1) fluorometric drug discovery kit
Supplier: ENZO LIFE SCIENCES
A QuantiZyme™ Assay System. The MMP-1 Fluorometric (also known as fluorimetric) Drug Discovery Kit is a complete assay system designed to screen inhibitors of matrix metalloproteinase-1 (MMP-1, interstitial collagenase) using a quenched fluorogenic peptide: OmniMMP™ fluorogenic substrate Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH. Mca fluorescence is quenched by the Dpa group until cleavage by MMPs at the Gly-Leu bond separates the two moieties.
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1-Stearoyl-2-arachidonoyl-sn-glycerol ≥95% (by TLC)
Supplier: ENZO LIFE SCIENCES
PKC activator.
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SB-366791 ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
A potent and selective vanilloid receptor (TRPV1) antagonist. An effective antagonist of hTRPV1 when stimulated by capsaicin, acid, or noxious heat.
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Anti-HSP70 Mouse Monoclonal Antibody [clone: C92F3A-5]
Supplier: ENZO LIFE SCIENCES
The Hsp70 family of heat shock proteins contains multiple homologs ranging in size from 66-78 kDa, and are the eukaryotic equivalents of the bacterial DnaK. The most studied Hsp70 members include the cytosolic stress-induced Hsp70 (Hsp72), the constitutive cytosolic Hsc70 (Hsp73), and the ER-localized BiP (Grp78). Hsp70 family members contain highly conserved N-terminal ATP-ase and C-terminal protein binding domains. Binding of peptide to Hsp70 is assisted by Hsp40, and stimulates the inherent ATPase activity of Hsp70, facilitating ATP hydrolysis and enhanced peptide binding. Hsp70 nucleotide exchange and substrate binding coordinates the folding of newly synthesized proteins, the re-folding of misfolded or denatured proteins, coordinates trafficking of proteins across cellular membranes, inhibits protein aggregation, and targets the degradation of proteins via the proteasomal pathway.
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SMER28 (synthetic) ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Small molecule inducer of autophagy important for neurodegenerative disease research.
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9-cis-Retinoic acid ≥98% (by HPLC)
Supplier: ENZO LIFE SCIENCES
Retinoid X receptor ligand.
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ADAM Substrate
Supplier: ENZO LIFE SCIENCES
Fluorogenic substrate for ADAM8 (kcat/Km = 1,0×105 M-1s-1), ADAM10 (6,2×103), ADAM12 (2,8×105), TACE (TNF-α converting enzyme, ADAM17) (4,3×105), and likely other ADAMs, especially those that cleave TNF-α type sequences. Also efficiently cleaved by MMP-1, MMP-2, MMP-3, MMP-8, MMP-9, MMP-13, and MMP-14. FAM fluorescence is quenched by the Dabcyl group until cleavage separates them. Ex.: 485 nm, Em.: 530 nm. This substrate is useful for inhibitor screening and kinetic analysis.
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Anti-HMGB1 Mouse Monoclonal Antibody [clone: KS1]
Supplier: ENZO LIFE SCIENCES
The chromatin non-histone high mobility group of proteins (HMG)-1 and -2 contain conserved domains known as HMG-boxes. Both HMG-1 and HMG-2 contain an N-terminal HMG box, a central HMG box and an acidic carboxy terminus.
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Anti-NF-kappa B P65 Rabbit Polyclonal Antibody
Supplier: ENZO LIFE SCIENCES
Nuclear factor kappa-B (NFk) B) functions as a sequence specific transcriptional activator that binds to the intronic enhancer of kappa light chain gene in B lymphocytes. NF-kB is a heterodimer consisting of a 50 kDa DNA binding subunit (p50) and a 65 kDa transactivation subunit (p65/RelA) (ref. 3), both of which exhibit sequence homology to the protooncogene c-Rel. p50 has an isoform called p49/p52, and both proteins derive from the amino-terminal of precursor protein p105 and p100, respectively. The p50/p65 heterodimer remains in inactive form in the cytosol as a complex with its inhibitor, IkB. Upon stimulation of cells by a variety of stimuli, including lipopolysaccharide (LPS), pro-inflammatory cytokines like interleukin-1 and tumor necrosis factor, and viral infection, IkB becomes phosphorylated and degraded by the proteosome. The active NF-kB heterodimer translocates into the nucleus and induces gene expression.
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Anti-EIF2 alpha Rabbit Polyclonal Antibody
Supplier: ENZO LIFE SCIENCES
Anti-EIF2 alpha Rabbit Polyclonal Antibody
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L-161-982 ≥98% (by HPLC)
Supplier: ENZO LIFE SCIENCES
Prostanoid receptor ligand.
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Anti-SUMO1 Rabbit Polyclonal Antibody
Supplier: ENZO LIFE SCIENCES
Host: Rabbit
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Anti-BLM10 Rabbit Polyclonal Antibody
Supplier: ENZO LIFE SCIENCES
Blm10 (mammalian homolog PA200) is a large 246kDa regulatory protein that binds to the 20S proteasome core particle (CP). Blm10 recognizes pre-activated open gate CP which is assumed to exist in equilibrium with inactive closed gate CP. Blm10 distinguishes gate conformations, regulates CP activation, and has been shown to be involved in CP maturation.