12561 Results for: "ENZO LIFE SCIENCES"

Supplier: Enzo Life Sciences

Universal methylated DNA standard (mouse) with the included primers can be used in conjunction with Enzo blood and tissue methylation kit or the express methylation kits.

Supplier: Enzo Life Sciences

Gambogic Acid is a natural product isolated from Garcinia Hurburyi. It induces apoptosis in several tumor cell lines including T47D breast cancer cells and MGC-803 human gastric carcinoma cells but not in normal cells. Apoptosis induction proceeds via upregulation of bax and inhibition of bcl-2 expression.The target of gambogic acid has been identified as the transferrin receptor.

Supplier: Enzo Life Sciences

Negative control for integrin avß3 antagonist Cyclo [Arg-Gly-Asp-D-Phe-Val].

Supplier: Enzo Life Sciences

TLR4 activator.

Supplier: Enzo Life Sciences

Corticosterone EIA kit is a colorimetric competitive enzyme immunoassay kit for the quantitative determination of corticosterone in culture supernatants, faeces, plasma, serum, and saliva from any species.

Supplier: Enzo Life Sciences

TLR4 activator.

Supplier: Enzo Life Sciences

Kynurenine aminotransferase inhibitor

Supplier: Enzo Life Sciences

XIAP (X-linked inhibitor of apoptosis) belongs to the IAP (inhibitors of apoptosis) family, which is characterized by one or more BIR (baculovirus IAP repeat) domains.

Supplier: Enzo Life Sciences

ProteoStat® Protein refolding and aggregation sensing kit provides a fractional factorial matrix design to facilitate screening of refolding parameters for a specific protein in different buffers, and a simple, homogenous assay format for monitoring protein aggregation using a red-emitting aggregation-sensitive dye. 

Supplier: Enzo Life Sciences

The GFP-Certified™ FluoForte™ Calcium Assay kit provides a homogeneous fluorescence-based assay for detecting intracellular calcium mobilization across a broad spectrum of biological targets.

Supplier: Enzo Life Sciences

The PROTEOSTAT® PDI assay kit provides a simple, homogenous assay for screening modulators of PDI enzymatic activity. This is accomplished by monitoring PDI-catalyzed reduction of insulin in the presence of Dithiothreitol (DTT), resulting in the formation of insulin aggregates which then bind avidly to the red-emitting fluorogenic PROTEOSTAT® PDI detection dye.

Supplier: Enzo Life Sciences

Recommended Applications: Flow Cytometry, IF

Species reactivity:

Supplier: Enzo Life Sciences

Red 580 dUTP (lyophilised)

Supplier: Enzo Life Sciences

Adenylate cyclase inhibitor (IC50=250 µM).

Supplier: Enzo Life Sciences

Polyunsaturated fatty acid.

Supplier: Enzo Life Sciences

Adenylate cyclase activator

Supplier: Enzo Life Sciences

PKA activator.

Supplier: Enzo Life Sciences

A cell-permeable cGMP antagonist which is resistant to hydrolysis by cyclic nucleotide phosphodiesterases (Ki=0.5 µM). No metabolic side effects. Significantly more lipophilic and membrane permeant as compared to Rp-cGMPS or Rp-8-Br-cGMPS

Supplier: Enzo Life Sciences

p23 is a ubiquitous, highly conserved co-chaperone for Hsp90 that participates in the folding of a number of cell regulatory proteins including progesterone and glucocorticoid receptors, HSF1, and telomerase. p23 is thought to modulate Hsp90 activity in the last stages of the chaperoning pathway by binding and stabilizing Hsp90 in its ATP-bound state.

Supplier: Enzo Life Sciences

Grp75 (Glucose regulated 75 kDa protein) is a member of the Hsp70 family. It is localized in the mitochondrial matrix, where, in concert with Hsp60, is thought to participate in the re-folding of proteins translocated into this organelle. Like its E. coli homolog DnaK, Grp75 possesses a cation-dependent ATPase activity thought to be central to its function as a chaperone.

Supplier: Enzo Life Sciences

CaM kinase inhibitor

Supplier: Enzo Life Sciences

Cytochrome P450 inhibitor

Supplier: Enzo Life Sciences

Cell-permeable PKC inhibitor. Selective for PKC (IC50=10nM) over CaM kinase II (IC50=17µM) and PKA (IC50=0.9µM). Induces apoptosis in various cell lines.

Supplier: Enzo Life Sciences

Produced in E. coli. Untagged rat nNOS.

Supplier: Enzo Life Sciences

Recombinant PI31 has been shown to compete with the proteasome regulators PA28 and 19S PA700 for binding to 20S, indicating that PI31 binds the 20S α-rings and may function by hindering substrate access to the 20S catalytic channel.

Supplier: Enzo Life Sciences

Host: Mouse, Isotype: IgG1

Supplier: Enzo Life Sciences

Simple assay to quantify senescence-associated β-galactosidase activity, in live cells, using flow cytometry or fluorescent microscopy.

Supplier: Enzo Life Sciences

CDK inhibitor

Supplier: Enzo Life Sciences

BID is a cytosolic protein that is cleaved by caspase-8 in response to death receptor stimulation.

Supplier: Enzo Life Sciences

The caspases are a family of cysteine proteases that cleave after certain aspartate residues, and are primarily recognized as mediators of apoptosis. caspases are synthesized as inactive zymogens that can be cleaved to form active enzymes following the induction of apoptosis by stress or death receptors. Initiator caspases (e.g. caspase-8 and -10) are activated by dimerization of the zymogen on a dedicated adaptor protein. These activated initiator caspases in-turn cleave downstream effector or executioner caspases (e.g. caspase-3, -6, and -7) in a cascade-like manner, which cleave key cellular proteins that lead to the morphological changes associated with apoptotic cell death.