- Pk:0,05 mg
- Enzyme type:Recombinant
- Source:E. coli
- Species:Human
- Environmentally Preferable:
- Tag sequence:N-6 His tag
- Storage conditions:Store at −20 °C, stable for 6 months after receipt, please minimise freeze - thaw cycles
- Endotoxin content:<0,1 ng/µg (1 IEU/µg) as determined by LAL test
- Enzyme name:Aldehyde dehydrogenase 1-A3
- Enzyme synonyms:Aldehyde dehydrogenase family 1 member A3, ALDH1A3, Aldehyde dehydrogenase 6, Retinaldehyde dehydrogenase 3, RALDH-3, ALDH6
- Purity:>95% as determined by reducing SDS-PAGE
- Molecular weight:57,5 kD
- Sequence:Met1-Pro512
- Formulation:Supplied as a 0,2 µm filtered solution of 20 mM TrisHCl, 150 mM NaCl, pH 7,5, 20% Glycerol.
Aldehyde dehydrogenase 1 family member A3 (ALDH1A3), also known as retinaldehyde dehydrogenase 3 (RALDH3), is a member of the aldehyde dehydrogenase family known to metabolise a wide variety of aldehydes.
This recombinant protein can be used for biological assays. For research use only.
Fusion-Tag: N-6 His tag
ALDH1A3 specifically oxidises retinal to retinoic acid (RA) and is differentially expressed in developing embryonic tissues and adult organs. The RA produced by ALDH1A3 in rodents contributes to the development of skin and hair follicles, brain, tooth buds, lungs, olfactory bulbs, kidneys, eyes, skeletal muscle and seminal vesicles. In recent research, ALDH1A3 could be as a marker of cancer stem cell to predict metastasis or clinical prognosis in many cancers.