Specifications
- Antibody type:Primary
- Antigen name:TP/thymidine phosphorylase
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 680
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Reactivity:Human
- Western blot:Yes
- Epitope:121-220/482
- Form:Liquid
- Gene ID:1890
- Antigen synonyms:TYPH_HUMAN|TP|PDEGF|Endothelial cell growth factor 1 platelet derived|hPD ECGF|TdRPase|MNGIE|Gliostatin|TYMP|ECGF 1|PDECGF|ECGF1|PD ECGF|Platelet derived endothelial growth factor|Thymidine Phosphorylase|Endothelial cell growth factor 1
- Modification:Unmodified
- Storage buffer:Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
- Molecular weight:50 kDa
- Storage temperature:Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentration:1 µg/µl
- Shipping temperature:4 °C
- Immunogen:KLH conjugated synthetic peptide derived from human Thymidine Phosphorylase
- Tested applications:ICC
- Purification:Purified by Protein A
- Pack type:Vial
- Pk:100 µl
Specifications
About this item
In the presence of inorganic orthophosphate, the platelet-derived endothelial growth factor (PD-ECGF) thymidine phosphorylase (TP) (gliostatin) catalyses the reversible phospholytic cleavage of thymidine and deoxyuridine to their corresponding bases and 2-deoxyribose-1-phosphate. It is both chemotactic and mitogenic for endothelial cells and a non-heparin binding angiogenic factor present in platelets. It is also involved in transformation of fluoropyrimidines, cytotoxic agents used in the treatment of a variety of malignancies, into active cytotoxic metabolites.
Type: Primary
Antigen: TP/thymidine phosphorylase
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 680
Public Immunogen Range: 121-220/482
Host: Rabbit
Isotype: IgG
Reactivity: Human