Human Recombinant IL-10 (from E. coli)

Supplier: Shenandoah Biotechnology

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Supplier: Shenandoah Biotechnology

About this item

Interleukin 10 (IL-10) is an anti-inflammatory cytokine produced by macrophages and type 2 T helper (Th2) cells. IL-10 inhibits the production of pro-inflammatory cytokines such as interferon gamma (IFN-ɣ), tumor necrosis factor alpha (TNF-α), interleukin 2 (IL-2), interleukin 3 (IL-3), interleukin 4 (IL-4), and granulocyte-macrophage colony-stimulating factor (GM-CSF), made by macrophages and regulatory T cells. IL-10 also suppresses antigen presentation on antigen presenting cells, and enhances the survival, proliferation, and antibody production of B cells. Human IL-10 can act on murine cells, while murine IL-10 is not active on human cells.

High quality
Low endotoxin
Affordable

Caution: This product is for research use only and is not for use in humans.

Specifications

Conjugaison:
Unconjugated
Fonction des protéines:
Cytokine
Type de protéine/peptide:
Recombinant
Source:
E. coli
Species:
Human
Conditions de stockage:
–20 °C
Teneur en endotoxines:
Endotoxin LAL (EU/µg) ≤0,1
Activité biologique:
Bioactivity Assay: MC/9 cell Proliferation, ED₅₀ ≤5 ng/ml, Bioactivity ≥2,0×10⁵ units/mg
ID de gène:
P22301
Reconstitution instructions:
Sterile water at 0,1 mg/ml
Exempt d'endotoxine:
N
Sans vecteur:
Y
Exempt de protéase:
N
Exempt de substance animale:
Y
Synonyme de protéine:
B-TCGF|TGIF|CSIF
Nom de la protéine/du peptide:
IL-10 (AF)
Purity:
≥97%
Molecular weight:
18,8 kDa
Sequence:
MSPGQGTQSE NSCTHFPGNL PNMLRDLRDA FSRVKTFFQM KDQLDNLLLK ESLLEDFKGY LGCQALSEMI QFYLEEVMPQ AENQDPDIKA HVNSLGENLK TLRLRLRRCH RFLPCENKSK AVEQVKNAFN KLQEKGIYKA MSEFDIFINY IEAYMTMKIR N
Niveau d'endotoxine:
Low
Formulation:
10 mM Sodium phosphate, pH 7,5
Absence de nucléases:
N
N°:
RUO
Température de transport:
RT
Tested applications:
Bioassay