Human recombinant thrombopoietin (from cells)
PRSI92-493
:
- Pk:50 µG
- Protein/peptide type:Recombinant
- Source:Cells
- Species:Human
- Tag sequence:N, C-6 His tag
- Storage conditions:Lyophilized protein should be stored at −20 °C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7 °C for 2-7 days. Aliquots of reconstituted samples are stable at −20 °C for 3 months.
- Protein synonyms:TPO|C-mpl ligand|THPO|Myeloproliferative leukemia virus oncogene ligand|Megakaryocyte colony-stimulating factor|Megakaryocyte growth and development factor|Thrombopoietin
- Protein/peptide name:Thrombopoietin
- Purity:> 95% as determined by reducing SDS-PAGE
- Molecular weight:37.3 kD
- Sequence:Ser22-Gly353
- Formulation:Lyophilized from a 0.2 um filtered solution of 20mM Tris,150mM NaCl,pH 8.0. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the Lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Thrombopoietin (TPO) is a glycoprotein hormone which belongs to the EPO/TPO family. It produced by the liver and kidney which regulates the production of platelets. TPO stimulates the production and differentiation of megakaryocytes, the bone marrow cells that bud off large numbers of platelets. Lineage-specific cytokine affects the proliferation and maturation of megakaryocytes from their committed progenitor cells. It acts at a late stage of megakaryocyte development. It may be the major physiological regulator of circulating platelets.
Fusion-Tag: N, C-6 His tag
This recombinant protein can be used for biological assays. For research use only.