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Human recombinant myelin P0-like 1 (from cells)
Human recombinant myelin P0-like 1 (from cells)
Catalog # PRSI92-390
Supplier:  ProSci Inc.
CAS Number:  
Human recombinant myelin P0-like 1 (from cells)
Catalog # PRSI92-390
Supplier:  ProSci Inc.
CAS Number:  

Specifications

  • Pk:
    50 µG
  • Protein/peptide type:
    Recombinant
  • Source:
    Cells
  • Species:
    Human
  • Tag sequence:
    C-6 His tag
  • Storage conditions:
    Lyophilized protein should be stored at −20 °C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7 °C for 2-7 days. Aliquots of reconstituted samples are stable at −20 °C for 3 months.
  • Protein synonyms:
    transcript variant 1|isoform CRA_b|highly similar to Homo sapiens myelin protein zero-like 1 (MPZL1)|cDNA FLJ78597|FLJ96614|Homo sapiens myelin protein zero-like 1 (MPZL1)|Mrna|Myelin protein zero-like 1|MPZL1|cDNA|mRNA
  • Protein/peptide name:
    Myelin P0-like 1
  • Purity:
    > 95% as determined by reducing SDS-PAGE
  • Molecular weight:
    15.2 kD
  • Sequence:
    Ser36-Val162
  • Formulation:
    Lyophilized from a 0.2 um filtered solution of 20mM PB,150mM NaCl,pH7.4. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the Lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
  • Tested applications:
    Bioassay

Specifications

About this item

Myelin protein zero-like protein 1(MPZL1) is encoded by the MPZL1 gene, which is a single-pass type I membrane protein. It is widely expressed with highest levels in heart, placenta, kidney and pancreas. As cell surface receptor, it involved in signal transduction processes. MPZL1 recruits PTPN11/SHP-2 to the cell membrane and subsequently activate/phosphorylate Src kinase at Tyr426, promoting phosphorylation of cortactin and migration of HCC cells. MPZL1also is a major receptor for concanavalin-A (ConA) and involved in cellular signalling induced by ConA, which probably includes Src family tyrosine-protein kinases.

Fusion-Tag: C-6 His tag

This recombinant protein can be used for biological assays. For research use only.