Human recombinant LILRB2 (from HEK293 cells)
Catalog # PRSI96-515
Supplier: ProSci Inc.
CAS Number:
Specifications
- Pk:100 µG
- Protein/peptide type:Recombinant
- Source:HEK293 cells
- Species:Human
- Environmentally Preferable:
- Biological activity:Measured by its ability of the immobilized protein to support the adhesion of HSB2 human peripheral blood acute lymphoblastic leukemia cells. When 80000 cells/well are added to LILRB2 coated plates (8. 8μg/mL with 100μL/well), > 40% cells will adhere for 1 hour incubation at 37˚C.
- Protein synonyms:CD85d|ILT4|LILRB2|LIR2|MIR10
- Protein/peptide name:LILRB2
- Purity:>92% as determined by SDS-PAGE.
- Molecular weight:48.6 kDa
- Formulation:Lyophilized, PBS, pH7.4
- Tested applications:Western Blot
Specifications
About this item
Leukocyte immunoglobulin-like receptor subfamily B member 2 (LILRB2) is also known as CD85 antigen-like family member D (CD85d), Immunoglobulin-like transcript 4 (ILT-4), Monocyte / macrophage immunoglobulin-like receptor 10 (MIR-10), which is a member of the the subfamily B class of LIR receptors. LILRB2 is receptor for class I MHC antigens. LILRB2 recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. LILRB2 competes with CD8A for binding to class I MHC antigens. LILRB2 / CD85d inhibits FCGR1A-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions.