Specifications

Antibody type:
Primary
Antigen name:
Transient Receptor Potential Cation Channel Subfamily M member 7
Antigen symbol:
TRPM7
Clonality:
Polyclonal
Conjugation:
FITC (Fluorescein Isothiocyanate)
Host:
Rabbit
ImmunoChemistry:
Yes
Isotype:
IgG
Reactivity:
Human,
Rat,
Mouse
Cross adsorption:
No
Form:
liquid
Gene ID:
54822
Antigen synonyms:
TRPPLIK|CHAK1|LTrpC-7|2310022G15Rik|Ltrpc7|Ltpr7|CHAK|4833414K03Rik|5033407O22Rik
Storage buffer:
Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Storage temperature:
Store at –20 °C for 12 months
Concentration:
1 μg/μl
Shipping temperature:
4°C
Immunogen:
800-850/1865
Purification:
Purified by Protein A
Pk:
100 µl

Specifications

About this item

Essential ion channel and serine/threonine-protein kinase. Divalent cation channel permeable to calcium and magnesium. Has a central role in magnesium ion homeostasis and in the regulation of anoxic neuronal cell death. Involved in TNF-induced necroptosis downstream of MLKL by mediating calcium influx. The kinase activity is essential for the channel function. May be involved in a fundamental process that adjusts plasma membrane divalent cation fluxes according to the metabolic state of the cell. Phosphorylates annexin A1 (ANXA1).

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: TRPM7
Clonality: Polyclonal
Clone:
Conjugation: FITC (Fluorescein Isothiocyanate)
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat