BCL10, with an N-terminal caspase recruitment domain (CARD), is found in a number of apoptotic regulatory molecules. It was identified through its direct involvement in t(1;14) of mucosa-associated lymphoid tissue (MALT) lymphoma. Expression of BCL10 was shown to induce NFkB activation in a NIK-dependent pathway. This MAb labels subpopulations of normal B and T cells and is a useful tool for the sub-classification of lymphomas. In MALT lymphomas with the t(1;14) translocation, while 55% of MALT lymphomas lacking this translocation exhibited the same labeling pattern, although at a much lower level.
Type: Primary
Antigen: BCL10
Clonality: Monoclonal
Clone: BL10/411
Conjugation: CF647
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Human
- Catalog No:
- BNC470411-100
- BNC470411-500
- Antigen symbol:
- BCL10
- BCL10
- Antigen name:
- BCL-10
- BCL-10
- Antibody type:
- Primary
- Primary
- Clonality:
- Monoclonal
- Monoclonal
- Conjugation:
- CF® 647
- CF® 647
- Clone:
- Clone BL10/411
- Clone BL10/411
- Reactivity:
- Human
- Human
- Host:
- Mouse
- Mouse
- Gene ID:
- 193516
- 193516
- Isotype:
- IgG1 kappa
- IgG1 kappa
- Western blot:
- Yes
- Yes
- ImmunoChemistry:
- Yes
- Yes
- ImmunoFluorescence:
- Yes
- Concentration:
- 0,1 mg/ml
- 0,1 mg/ml
- Storage buffer:
- PBS/0,1% BSA/0,05% azide
- PBS/0,1% BSA/0,05% azide
: VWR Chemicals
: VWR Collection
: VWR Collection
: VWR Chemicals
: VWR Collection
: VWR Collection
: KIMBERLY CLARK
: VWR Collection