Primary human coronary artery endothelial cells (HCAEC) are isolated from the coronary arteries (the right and the left coronary artery, including the anterior descending and the circumflex branches) from a single donor.

These cells are involved in the regulation of coronary blood flow and cardiac functions and are consequently useful for in vitro studies of diseases such as thrombosis, atherosclerosis and hypertension and also suitable for studying functional vaso-dilators such as prostacyclin, bradykinin or nitric oxide.