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Nucleic Acid Reagents

Nucleic acid reagents form the foundation of genetic analysis and molecular biology, playing a pivotal role from cloning to gene expression studies. Delve into our collection featuring high-fidelity enzymes for end-point PCR, advanced reagents for isothermal amplification, and comprehensive kits for nucleic acid purification. For precision in quantitative assays, explore our selection of qPCR and RT-qPCR kits, primed for unparalleled accuracy. Our portfolio also includes next-generation sequencing reagents, offering cutting-edge solutions for genomic sequencing and personalized medicine advancements.

TriLink® 2'-Deoxy-P-nucleoside-5'-Triphosphate

TriLink® 2'-Deoxy-P-nucleoside-5'-Triphosphate

Supplier: TriLink BioTechnologies

2'-Deoxy-P-nucleoside is a degenerate base which behaves as a universal pyrimidine and therefore base pairs with both adenine and guanine. This feature makes it a powerful tool in mutagenesis studies.

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TriLink® 2',3'-Dideoxyguanosine-5'-O-(1-Thiotriphosphate)

TriLink® 2',3'-Dideoxyguanosine-5'-O-(1-Thiotriphosphate)

Supplier: TriLink BioTechnologies

2',3'-Dideoxyguanosine-5'-O-(1-Thiotriphosphate) is a sugar modified nucleoside triphosphate where the 2' and 3' hydroxyl groups are absent, resulting in chain termination. This ddGTP analog also contains a 1-Thiotriphosphate which results in a nuclease resistant phosphorothioate linkage. The inability of polymerases to extend from a dideoxy nucleotide causes chain termination and is useful in antiviral research and in a variety of biotechnology applications.

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TriLink® 2',3'-Dideoxythymidine-5'-O-(1-Thiotriphosphate)

TriLink® 2',3'-Dideoxythymidine-5'-O-(1-Thiotriphosphate)

Supplier: TriLink BioTechnologies

2',3'-Dideoxythymidine-5'-O-(1-Thiotriphosphate) is a sugar modified nucleoside triphosphate where the 2' and 3' hydroxyl groups are absent, resulting in chain termination. This ddTTP analog also contains a 1-Thiotriphosphate which results in a nuclease resistant phosphorothioate linkage. The inability of polymerases to extend from a dideoxy nucleotide causes chain termination and is useful in antiviral research and in a variety of biotechnology applications.

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TriLink® Cytidine-5'-O-(1-Thiotriphosphate)

TriLink® Cytidine-5'-O-(1-Thiotriphosphate)

Supplier: TriLink BioTechnologies

TriLink® Cytidine-5'-O-(1-Thiotriphosphate)

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TriLink® N6-Methyladenosine-5'-Triphosphate

TriLink® N6-Methyladenosine-5'-Triphosphate

Supplier: TriLink BioTechnologies

N6-methyl adenosine (N6-methyl ATP) is a base modified analog of adenosine and is found as a minor nucleoside in natural RNAs (Meyer et al.). N6-methyl ATP can substitute for ATP in some biological systems, and is a potent agonist for P2Y-purinoceptors in the guinea pig, taenia coli (Burnstock et al.).

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Fluorescein-12-ddUTP dideoxynucleotide pack for 3’-oligonucleotide labeling

Supplier: ENZO LIFE SCIENCES

The procedure for labeling of DNA probes with a polynucleotide 'tail' containing hapten-labeled nucleotides was developed by Enzo. In such terminal labeling reactions, terminal transferase catalyzes the addition of nucleotides to any 3'-OH terminus in a template independent manner. This rapid and convenient nonradioactive labeling procedure is free of any sequence bias that is normally observed in random priming or nick translation reactions.

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TriLink® N1-Methyl-2'-O-Methylpseudouridine-5'-Triphosphate

TriLink® N1-Methyl-2'-O-Methylpseudouridine-5'-Triphosphate

Supplier: TriLink BioTechnologies

TriLink® N1-Methyl-2'-O-Methylpseudouridine-5'-Triphosphate

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SLK Human siRNA Oligo Duplex (Locus ID 9748)

Supplier: OriGene

This SLK Human siRNA Oligo Duplex mediates apoptosis and actin stress fiber dissolution.

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Digoxigenin-dUTP, alkali-stable

Digoxigenin-dUTP, alkali-stable

Supplier: ENZO LIFE SCIENCES

Digoxigenin-labeled nucleotide suitable for non-radioactive labeling of DNA probes.

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TriLink® 5-Methoxyuridine-5'-Triphosphate

TriLink® 5-Methoxyuridine-5'-Triphosphate

Supplier: TriLink BioTechnologies

This nucleotide consists of a modified base, a ribose, and a 5′ triphosphate group.

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TriLink® 5-Methyluridine-5'-Triphosphate

TriLink® 5-Methyluridine-5'-Triphosphate

Supplier: TriLink BioTechnologies

TriLink® 5-Methyluridine-5'-Triphosphate

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TriLink® N1-Methoxymethylpseudouridine-5'-Triphosphate

TriLink® N1-Methoxymethylpseudouridine-5'-Triphosphate

Supplier: TriLink BioTechnologies

TriLink® N1-Methoxymethylpseudouridine-5'-Triphosphate

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TriLink® Adenosine-5'-Triphosphate

TriLink® Adenosine-5'-Triphosphate

Supplier: TriLink BioTechnologies

This nucleotide consists of an unmodified base, a ribose, and a 5′ triphosphate group for synthesis of RNA molecules.

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TriLink® Cytidine-5'-Triphosphate

TriLink® Cytidine-5'-Triphosphate

Supplier: TriLink BioTechnologies

This nucleotide consists of an unmodified base, a ribose, and a 5′ triphosphate group for synthesis of RNA molecules.

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TriLink® Uridine-5'-O-(1-Thiotriphosphate)

TriLink® Uridine-5'-O-(1-Thiotriphosphate)

Supplier: TriLink BioTechnologies

TriLink® Uridine-5'-O-(1-Thiotriphosphate)

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TriLink® 2'-O-Methyluridine-5'-Triphosphate

TriLink® 2'-O-Methyluridine-5'-Triphosphate

Supplier: TriLink BioTechnologies

TriLink® 2'-O-Methyluridine-5'-Triphosphate

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TriLink® Biotin-7-Deaza-7-Propargyl-dGTP

TriLink® Biotin-7-Deaza-7-Propargyl-dGTP

Supplier: TriLink BioTechnologies

TriLink® Biotin-7-Deaza-7-Propargyl-dGTP

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TriLink® N1-Ethylpseudouridine-5'-Triphosphate

TriLink® N1-Ethylpseudouridine-5'-Triphosphate

Supplier: TriLink BioTechnologies

A modified NTP for incorporation into messenger RNAs (mRNA) using T7 RNA Polymerase. Incorporation of N1-ethylpseudouridine can reduce the immunogenicity of the resulting mRNA.

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TriLink® 2'-Fluoro-2'-deoxyuridine-5'-Triphosphate

TriLink® 2'-Fluoro-2'-deoxyuridine-5'-Triphosphate

Supplier: TriLink BioTechnologies

2'-Fluoro NTPs are being utilised in an increasing number of applications in research and new drug development. 2'-Fluoro-dUTP is incorporated in both DNA and RNA constructs to improve in vivo stability.

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AMPIGENE® dNTP Mix

Supplier: ENZO LIFE SCIENCES

Ultra-pure, stable, and suitable for a variety of PCR applications.

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TriLink® Biotin-16-Aminoallyl-2'-deoxyuridine-5'-Triphosphate

TriLink® Biotin-16-Aminoallyl-2'-deoxyuridine-5'-Triphosphate

Supplier: TriLink BioTechnologies

Biotin-16-Aminoallyl-2'-deoxyuridine can be enzymatically incorporated into DNA via PCR, nick translation, primer extension using Klenow(exo-) DNA polymerase, and terminal deoxynucleotidyl transferase (TdT). Biotinylated cDNA can be prepared with this NTP using Moloney Murine Leukemia Virus (M-MLV) reverse transcriptase.

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TriLink® 2'-Deoxycytidine-5'-Triphosphate

TriLink® 2'-Deoxycytidine-5'-Triphosphate

Supplier: TriLink BioTechnologies

This nucleotide consists of an unmodified base, a deoxyribose, and a 5′ triphosphate group for synthesis of DNA molecules.

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TriLink® 2'-Deoxyguanosine-5'-Triphosphate

TriLink® 2'-Deoxyguanosine-5'-Triphosphate

Supplier: TriLink BioTechnologies

This nucleotide consists of an unmodified base, a deoxyribose, and a 5′ triphosphate group for synthesis of DNA molecules.

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TriLink® CleanAmp® 7-Deaza-dGTP

TriLink® CleanAmp® 7-Deaza-dGTP

Supplier: TriLink BioTechnologies

CleanAmp® dNTPs are chemically-modified nucleotides designed to improve specificity, sensitivity, and robustness of your PCR.

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TriLink® 5-Methylcytidine-5'-Triphosphate

TriLink® 5-Methylcytidine-5'-Triphosphate

Supplier: TriLink BioTechnologies

This nucleotide consists of a modified base, a ribose, and a 5′ triphosphate group.

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Dideoxyuridine triphosphates (ddUTPs)

Supplier: ENZO LIFE SCIENCES

These ddUTPs are used for 3’-end labeling of oligodeoxynucleotides using terminal transferase. ddUTP also serves as a substrate for E. coli DNA Polymerase I (holoenzyme and Klenow fragment), T4 and T7 DNA polymerases, Taq DNA polymerase and reverse transcriptase.

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PPM1B Human siRNA Oligo Duplex (Locus ID 5495)

Supplier: OriGene

The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways.

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Fluorescent nucleotides, Red 594 dUTP and Red 598 dUTP

Supplier: ENZO LIFE SCIENCES

Red dUTP's (Red 594 dUTP, Red 598 dUTP) can replace TTP in reactions in which it serves as a substrate for E. coli DNA polymerase (holoenzyme and Klenow fragment), T4 and Taq DNA polymerases, reverse transcriptase (from AMV and M-MuLV) and terminal transferase.

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5-Tetramethylrhodamine-dUTP, 1 mM Solution

Supplier: Biotium

5-TAMRA-dUTP (5-Tetramethylrhodamine-dUTP) can be enzymatically incorporated into DNA to make fluorescently labeled probes, and has absorption/emission at 553/577 nm. Note: 5-TAMRA-dUTP may not be compatible with PCR labeling of DNA probes. Supplied as a 1 mM solution in Tris-HCl buffer, pH 7.5.

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TriLink® Biotin-16-Aminoallyluridine-5'-Triphosphate

TriLink® Biotin-16-Aminoallyluridine-5'-Triphosphate

Supplier: TriLink BioTechnologies

Biotin-16-Aminoallyluridine-5'-Triphosphate (Biotin-16-UTP, Biotin-16-AA-UTP) can be incorporated via a number of RNA polymerases, including SP6-, T3- and T7-RNA polymerase to form labeled RNA.

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