You searched for: Amiloride hydrochloride

Supplier: Merck Millipore (Calbiochem‎)

This is an inhibitor of angiogenesis. Inhibits capillary morphogenesis completely and reversibly at approximately 130 µM. At low concentrations, acts as a potent and specific inhibitor of transmembrane Na⁺ entry and Na⁺, K⁺-ATPase. Blocks smooth muscle responses to contractile stimuli and palytoxin-induced conductance in skeletal muscle.

Supplier: Cayman Chemical

Amiloride is a potassium-sparing diuretic that promotes the loss of sodium and water from the body by directly blocking sodium reabsorption through epithelial sodium channels. Amiloride can also block Na⁺/H⁺ exchangers in the heart, which can serve to minimize reperfusion injury in ischemic attacks. Additionally, acid-sensing ion channels, which are involved in nociceptor responses to pH, can also be inhibited by amiloride.